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Diss Factsheets
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EC number: 222-264-8 | CAS number: 3398-33-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_toxicological-information.png)
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 21/03/2002
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 002
- Report date:
- 2012
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 401 (Acute Oral Toxicity)
- GLP compliance:
- yes
- Test type:
- acute toxic class method
Test material
- Reference substance name:
- Sodium undec-10-enoate
- EC Number:
- 222-264-8
- EC Name:
- Sodium undec-10-enoate
- Cas Number:
- 3398-33-2
- Molecular formula:
- C11H20O2.Na
- IUPAC Name:
- sodium undec-10-enoate
Constituent 1
- Specific details on test material used for the study:
- sodium undec-10-enoate in a 33.2% aqueous solution administered at 2000mg/kg corresponds to 664 mg/kg of pure sodium undec-10-enoate.
Test animals
- Species:
- rat
- Strain:
- Sprague-Dawley
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- 5 males and 5 females
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- unchanged (no vehicle)
- Details on oral exposure:
- The test substance was administered to a group of 10 fasted Sprague-Dawley rats (5 males and 5 females). The administration was performed with the test substance in its original form (sodium undec-10-enoate in a 33.2% aqueous solution) at a dose level of 2000 mg/kg (corresponds to 664 mg/kg of pure sodium undec-10-enoate) taking into consideration that the specific gravity of the test substance was 1.032.
- Doses:
- 2000 mg/kg
- No. of animals per sex per dose:
- 5 males and 5 females
- Control animals:
- no
- Details on study design:
- the mortality, general behaviour and bodyweight gain of the animals were observed for a period of 14 days after the sigle administration of the test substance . A necropsy was performed on each animal sacrificed at the end of the study.
Results and discussion
Effect levels
- Key result
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- >= 664 mg/kg bw
- Based on:
- test mat.
- Mortality:
- no mortality at the dose level of 664 mg/kg of sodium undec-10-enoate.
- Clinical signs:
- other: the general behaviour of the animals was not influenced by the treatment.
- Gross pathology:
- The macroscopic examination revealed no abnormality in the animals sacrificed at the end of the study.
Applicant's summary and conclusion
- Interpretation of results:
- Category 4 based on GHS criteria
- Conclusions:
- sodium undec-10-enoate (in a 33.2% aqueous solution) administered by oral route in the Rat was higher than 2000 mg/kg, i.e. higher than 664 mg/kg of pure sodium undec-10-enoate. No signs of toxicity were observed at this dose level.
- Executive summary:
The acute oral toxicity study was performed according to the OECD 401 guideline. The substance sodium undec-10-enoate (in a 33.2% aqueous solution) administered by oral route in the Rat was higher than 2000 mg/kg, i.e. higher than 664 mg/kg of pure sodium undec-10-enoate. No signs of toxicity were observed at this dose level.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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