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EC number: 263-134-0 | CAS number: 61790-41-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Study period:
- February 02, 2018
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
- Reason / purpose for cross-reference:
- reference to other study
- Reason / purpose for cross-reference:
- reference to other study
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Version / remarks:
- Calculated from individual solubilities in water and n-octanol, as the test substance is surface active
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - HPLC Method)
- Version / remarks:
- Calculated from individual solubilities in water and n-octanol, as the test substance is surface active
- GLP compliance:
- not specified
- Type of method:
- estimation method (solubility ratio)
- Partition coefficient type:
- octanol-water
- Analytical method:
- other: Not applicable
- Key result
- Type:
- log Pow
- Partition coefficient:
- ca. 2.94
- Temp.:
- 20 °C
- Remarks on result:
- other: Calculation method based on solubility ratio (log of n-octanol solubility/CMC)
- Type:
- log Pow
- Partition coefficient:
- ca. -0.266
- Temp.:
- 20 °C
- Remarks on result:
- other: Calculation method based on solubility ratio (log of n-octanol solubility/water solubility)
- Conclusions:
- Under study conditions, the partition coefficient of the test substance, TMAC S, was determined to be 2.94 at 20°C.
- Executive summary:
The partition coefficient of the test substance, TMAC S, was calculated from individual solubilities in water and n-octanol, according to a method specified in OECD Guideline 107 and EU Mehod A.8. The partition coefficient was determined by dividing the octanol solubility by the water solubility. The logarithm of this value is called the Log Pow. It was assumed that there are no changes in volume when mixing water or octanol with the test substance. The octanol solubility and water solubility were determined to be 260 and 480 g/L in the respective studies. Based on these values the log Pow was calculated to be at -0.266. However, considering the substance is a surfactant, a CMC based water solubility equivalent, which is considered to be practically more reliable value, was additionally determined at 300 mg/L at 20°C (Andersson, 2018). The log Pow using the n-octanol and CMC based water solubility was calculated at 2.94 at 20°C. Therefore, given that TMAC S is a surfactant, the CMC based log Pow has been considered further for hazard/risk assessment.
Reference
Results
Log Pow based on water solubility conducted according to OECD 105:
The octanol solubility and water solubility were determined to 260 g/L and 480 mg/L respectively, in earlier studies.
Log Pow = Log Octanol solubility/Water solubility = log 260/480 = -0.266
The Log Pow for Soya TMAC was determined to be -0.266.
Considering that the substance is a surfactant, the CMC based water solubility equivalent is considered to be a more reliable value. Therefore, the octanol solubility and water solubility (based on CMC) were determined to 260 g/L and 300 mg/L respectively, in earlier studies.
Log Pow = Log Octanol solubility/Water solubility = log 260/0.3 = 2.938
The Log Pow for Soya TMAC was determined to be 2.94.
Description of key information
The partition coefficient of the test substance was calculated from individual solubilities in water (as well as CMC) and n-octanol, according to a method specified in OECD Guideline 107 and EU Method A.8 (Andersson, 2018).
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 2.94
- at the temperature of:
- 20 °C
Additional information
The log Pow calculated based on n-octanol solubility and CMC ratio was 2.94 at 20°C; the log Pow calculated based on n-octanol and water solubility ratio was: -0.266 at 20°C. Therefore, considering that the substance is a surfactant, the log Pow (based on n-octanol solubility and CMC ratio) has been taken forward for the hazard and exposure assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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