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EC number: 221-029-7 | CAS number: 2978-58-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
not readily degradable
Additional information
Biodegradation in water: screening tests
The ready biodegradability of the test substance was investigated under GLP conditions by means of a CO2 Headspace Test, according to OECD guideline 310. The biodegradation of the test substance was followed by exposing it to microorganisms of non-adapted activated sludge from a municipal wastewater treatment plant. An inoculum control, containing sole pretreated activated sludge, a functional control with the reference substance aniline as well as a toxicity control, including both test item and reference item, was conducted simultaneously. The test concentration selected as appropriate was 20 mg/L TOC, corresponding to approximately 30 mg/L test substance. The flasks were incubated for 28 days at 22 ± 2 °C under aerobic and dark conditions. The biodegradability was derived from TIC analysis of the quantity of CO2 produced within the test period by respiration of bacteria. The mean value of degree of biodegradation was calculated by the single values of five test assays at the end of exposure with a limit of confidence of 95 %.
In result, the required pass level for ready biodegradability was not reached. The degree of biodegradation after an exposure period of 28 days was 0 ± 1 % TIC/TOC. As proven by the toxicity control, no inhibitory effects on microorganisms is expected at the tested concentration of 20 mg/L (degree of biodegradation after 28 days: 41 %).
In conclusion, the test item is not regarded to be in the 10-d-window or after 28 days to be readily biodegradable. Based on determined rate of biodegradation at the end of exposure the test item can be evaluated as poorly biodegradable in this test. All validity criteria were met and no deviations from the test guidelines or other incidents occurred during the course of the reported test which may have influenced. Based on this result, the test substance 1,1-dimethylprop-3-ynylaminehas to be regarded as not readily biodegradable.
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