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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

not sensitizing (read-across to sodium molybdate)

not sensitizing (read-across to ammonium dimolybdate)

Key value for chemical safety assessment

Skin sensitisation

Link to relevant study records

Referenceopen allclose all

Endpoint:
skin sensitisation: in vivo (non-LLNA)
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Justification for type of information:
Please refer to read-across justification attached in IUCLID Chapter 13.
Reason / purpose for cross-reference:
read-across source
Reading:
1st reading
Hours after challenge:
24
Group:
negative control
Dose level:
distilled water
No. with + reactions:
1
Total no. in group:
20
Clinical observations:
Slight erythema in one animal
Reading:
2nd reading
Hours after challenge:
48
Group:
negative control
Dose level:
distilled water
No. with + reactions:
0
Total no. in group:
20
Reading:
other: 3rd reading
Hours after challenge:
72
Group:
negative control
Dose level:
distilled water
No. with + reactions:
0
Total no. in group:
20
Reading:
1st reading
Hours after challenge:
24
Group:
test chemical
Dose level:
Ammonium dimolybdate, 45 % w/w in distilled water
No. with + reactions:
4
Total no. in group:
20
Clinical observations:
well-defined erythema in two animals; slight erythema in one animal: slight erythema and slight oedema in one animal
Reading:
2nd reading
Hours after challenge:
48
Group:
test chemical
Dose level:
Ammonium dimolybdate, 45 % w/w in distilled water
No. with + reactions:
4
Total no. in group:
20
Clinical observations:
Well-defined erythema in two animals; well-defined erythema and slight oedema in one animal; slight erythema in one animal
Reading:
other: 3rd reading
Hours after challenge:
72
Group:
test chemical
Dose level:
Ammonium dimolybdate, 45 % w/w in distilled water
No. with + reactions:
4
Total no. in group:
20
Clinical observations:
Well-defined erythema two animals; well-defined erythema and slight oedema in one animal; slight erythema in one animal
Endpoint:
skin sensitisation: in vivo (non-LLNA)
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Justification for type of information:
Please refer to read-across justification attached in IUCLID Chapter 13.
Reason / purpose for cross-reference:
read-across source
Reading:
1st reading
Hours after challenge:
24
Group:
negative control
Dose level:
distilled water
No. with + reactions:
0
Total no. in group:
20
Clinical observations:
None were found. There were no dermal reactions seen in the test animals that were considered to be evidence of a skin sensitisation response.
Reading:
2nd reading
Hours after challenge:
48
Group:
negative control
Dose level:
distilled water
No. with + reactions:
0
Total no. in group:
20
Clinical observations:
None were found. There were no dermal reactions seen in the test animals that were considered to be evidence of a skin sensitisation response.
Reading:
other: 3rd reading
Hours after challenge:
72
Group:
negative control
Dose level:
distilled water
No. with + reactions:
0
Total no. in group:
20
Clinical observations:
None were found. There were no dermal reactions seen in the test animals that were considered to be evidence of a skin sensitisation response.
Reading:
1st reading
Hours after challenge:
24
Group:
test chemical
Dose level:
Sodium molybdate 241/32, 70 and 35% w/w in distilled water
No. with + reactions:
0
Total no. in group:
20
Clinical observations:
None were found. There were no dermal reactions seen in the test animals that were considered to be evidence of a skin sensitisation response.
Reading:
2nd reading
Hours after challenge:
48
Group:
test chemical
Dose level:
Sodium molybdate 241/32, 70 and 35% w/w in distilled water
No. with + reactions:
0
Total no. in group:
20
Clinical observations:
None were found. There were no dermal reactions seen in the test animals that were considered to be evidence of a skin sensitisation response.
Reading:
other: 3rd reading
Hours after challenge:
72
Group:
test chemical
Dose level:
Sodium molybdate 241/32, 70 and 35% w/w in distilled water
No. with + reactions:
0
Total no. in group:
20
Clinical observations:
None were found. There were no dermal reactions seen in the test animals that were considered to be evidence of a skin sensitisation response.
Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available

Justification for classification or non-classification

Based on the data available and according to the criteria for classification and labeling laid down in Regulation (EC) 1272/2008, the test substance does not fulfill the classification criteria. Therefore, non-classification is warranted.