Registration Dossier
Registration Dossier
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EC number: 214-071-2 | CAS number: 1077-28-7
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 014
- Report date:
- 2014
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes
- Other quality assurance:
- ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
- Type of method:
- flask method
Test material
- Reference substance name:
- 5-(dithiolan-3-yl)valeric acid
- EC Number:
- 214-071-2
- EC Name:
- 5-(dithiolan-3-yl)valeric acid
- Cas Number:
- 1077-28-7
- Molecular formula:
- C8H14O2S2
- IUPAC Name:
- 5-(1,2-dithiolan-3-yl)pentanoic acid
- Reference substance name:
- unknown
- IUPAC Name:
- unknown
- Reference substance name:
- Water
- EC Number:
- 231-791-2
- EC Name:
- Water
- Cas Number:
- 7732-18-5
- Molecular formula:
- H2O
- IUPAC Name:
- dihydrogen oxide
- Test material form:
- solid: bulk
- Details on test material:
- This composition is the usual techical grade of AlzChem AG. It will be used when test substance has this composition (or is very closed) or no specific information is available
Constituent 1
impurity 1
impurity 2
Results and discussion
Water solubility
- Key result
- Water solubility:
- ca. 0.87 g/L
- Conc. based on:
- test mat.
- Temp.:
- 22 °C
- pH:
- > 3 - <= 3.6
Any other information on results incl. tables
Sample |
Result (g/l at 22 °C) |
Method |
1stsaturated solution |
0.87 |
HPLC |
2ndsaturated solution |
0.87 |
HPLC |
3rdsaturated solution |
0.88 |
HPLC |
Average |
0.87 |
(-) |
Applicant's summary and conclusion
- Conclusions:
- The average water solubility of alpha-Lipoic acid is 0.87 g/L at 22 °C.
- Executive summary:
The average water solubility of alpha-Lipoic acid is 0.87 g/L at 22 °C.
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