Registration Dossier
Registration Dossier
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EC number: 943-973-5 | CAS number: -
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- abstract
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 976
- Report date:
- 1976
Materials and methods
- Principles of method if other than guideline:
- No information available.
- GLP compliance:
- no
- Remarks:
- pre-GLP
Test material
- Reference substance name:
- Reaction products of 6-hydroxy-5-nitrosonaphthalene-2-sulfonic acid, chelated with iron (3+), sodium salts.
- EC Number:
- 943-973-5
- Molecular formula:
- not available being an UVCB substance
- IUPAC Name:
- Reaction products of 6-hydroxy-5-nitrosonaphthalene-2-sulfonic acid, chelated with iron (3+), sodium salts.
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- water
- Doses:
- 10-50 % acqueous suspensions.
- Control animals:
- not specified
- Details on study design:
- - Duration of observation period following administration: 14 days
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 1 500 - < 2 100 mg/kg bw
- Based on:
- test mat.
- Other findings:
- dyspnea, apathy, agitation, tumbling, cramps, partially belly-side position, tonic spasms, skin stained systemically green, urine stained green, intrabdominal colouration, general condition was bad.
Applicant's summary and conclusion
- Conclusions:
- 1500 mg/kg b.w.< LD50 ( mouse, i.p.) < 2100 mg/kg b.w.
- Executive summary:
Method
The acute toxicity, after intraperitoneal injection of the substance to mice, was evaluated. The animals were observed for 14 days.
Observations
The following signs were observed: dyspnea, apathy, agitation, tumbling, cramps, partially belly-side position, tonic spasms, skin stained systemically green, urine stained green, intrabdominal colouration, general condition was bad.
Results
The LD50 of the substance for the mouse over the period of 14 days is 1500 - 2100 mg/kg b.w.
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