Registration Dossier
Registration Dossier
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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 203-636-9 | CAS number: 108-99-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Guidance on Safe Use
Administrative data
First-aid measures
Skin Contact: Wash exposed area twice with soap and water. The exposed area should be examined by medical personnel if irritation or pain persists after the area has been washed. Remove/Take off immediately all contaminated clothing. Prolonged contact with contaminated clothing or shoes/boots may cause burns to appear after an extended exposure period.
Eye Contact: Rinse eyes immediately with large amounts of water for at least 15 minutes, occasionally lifting the eyelids. GET MEDICAL ATTENTION. Remove contact lenses if present and easy to do – continue rinsing.
Inhalation: Remove from exposure area to fresh air immediately. Keep at rest in a position comfortable for breathing. If breathing has stopped, give artificial respiration. GET MEDICAL ATTENTION.
Ingestion: Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER or doctor/physician immediately.
Do NOT induce vomiting, this material is corrosive. Give oxygen if respiration is shallow. GET MEDICAL ATTENTION. Do not give anything by mouth to an unconscious person.
Fire-fighting measures
Flammability Classification: Highly Flammable, Flammability Category 3.
Appropriate Extinguishing Media: Water, fog, Foam, Alcohol foam, Carbon dioxide, Dry chemical.
Hazardous Products of Combustion: Toxic fumes may be released upon thermal decomposition (cyanides, nitrogen oxides, carbon monoxide).
Potential for Dust Explosion: Not applicable.
Special Flammability Hazards: Not applicable.
Basic Fire Fighting Guidance: Wear self-contained breathing apparatus and full protective clothing (i.e., Bunker gear). Skin and eye contact should be avoided. Normal fire fighting procedures may be used.
Accidental release measures
Containment Techniques and Clean-up Procedures:
Isolate the hazard area and deny entry to unnecessary and unprotected personnel. Remove all ignition sources. Ventilate the area of spill or leak. Wear protective equipment during clean-up. For small spills, use suitable absorbent material and collect for later disposal.
For large spills, the area may require diking to contain the spill. Material can then be collected (e.g., suction) for later disposal. After collection of material, flush area with water. Dispose of the material in accordance with standard practice for disposal of potentially hazardous materials as required by applicable national, state or local laws.
Handling and storage
Keep container tightly closed.
Maintain cool, dry, ventilated conditions for storage. Should be periodically inspected.
Protect containers against physical damage.
Outside or detached storage is preferable. Inside storage should be in standard flammable liquids storage room or cabinet. Keep away from strong acids and oxidizing agents.
Keep away from heat/sparks/open flames/hot surfaces.
No smoking, eating, drinking.
Use explosion-proof electrical/ventilating/lighting/equipment.
Ground/bond container and receiving equipment.
Use only non-sparking tools. Take precautionary measures against static discharge.
Impervious secondary containment with volume greater than the largest container / vessel, closed systems, and bonded and grounded tanks, lines and vessels, applicable storage tank controls i.e. pressure and temperature gauging, pressure relief venting with routing to safe areas, applicable processing vessel controls, i.e. rupture discs with routing to overfill vessels of adequate capacity, ventilation for storage areas,
Processing in areas of good ventilation or in closed systems,
Transfers in closed, dedicated lines,
Electrical equipment with explosion proof rating.
Proper operations and storage conditions:
Controls to maintain the substance at appropriate temperature and pressure.
Isolation from uncontrolled heat sources, such as steam lines.
Monitor of substance vapor concentration prior to activities such as equipment maintenance and repair.
Implementation of formal hot work procedures.
Organization Controls
Written operating procedures for storage, transfer, substance use and emergency.
Training of employees on chemical process safety and emergency response.
Implementation of formal hot work procedures
Do not cut, weld , braze, solder, drill, grind or expose containers to heat, sparks, static electriciy, or other sources of ignition; they may explode
Access to SDS.
Other equipment, including fire control systems, consistent with and required for the storage and use of flammable materials.
Local Exhaust Ventilation: 90% efficiency minimum.
Environmental Risk Management Measures:
Compliance with local water discharge regulations.
Compliance with local air discharge regulations.
Impermeable surfaces.
Avoid release to the environment.
Keep away from drains / Do not empty into drains.
Substance must not enter sewage system.
This material and its container must be disposed in a safe way as a hazardous waste.
Practices to Minimize Risk:
Wear protective gloves/protective clothing/eye protection/face protection.
Do not breathe mist/vapours/spray.
Wear appropriate protective equipment when performing maintenance on contaminated equipment.
Wash hands thoroughly before eating or smoking after handling this material.
Dangerous Incompatibility Reactions:
Avoid contact with strong acids and oxidizing agents.
Incompatibilities with Materials of Construction:
May cause some forms of plastics and rubbers to deteriorate.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 2313
Shipping information
- Proper shipping name and description:
- Picolines
- Chemical name:
- 3-Picoline
- Language:
- English
Special provisions / remarks
- Special provisions:
- D/E Tunnel restriction
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- 2313
Shipping information
- Proper shipping name and description:
- Picolines
- Chemical name:
- 3-Picoline
- Language:
- English
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- 2313
Shipping information
- Proper shipping name and description:
- (beta-)Picolines
- Chemical name:
- 3-Picoline
- Labels:
- S-D; F-E
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- 2313
Shipping information
- Chemical name:
- 3-Picoline
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Personal Protective Equipment:
Use approved chemical cartridge-respirator or supplied air breathing equipment (Control efficiency: 95%).
Chemical goggles should be worn at all times; use face shields as conditions warrant.
Neoprene, nitrile or PVC-coated gloves.
Impervious clothing, protective clothing with long sleeves, and boots.
Ventilation: All operations should be conducted in well-ventilated conditions. Local exhaust ventilation should be provided to keep airborne concentrations below exposure limits.
Specific activity training including personal protective equipment requirements.
Local exhaust except outside unload : 90 % efficiency
Safety showers and eyewash stations in near vicinity
Prevent formation of aerosols
Contaminated work clothing should not be allowed out of workplace
Safety showers and eyewash stations in near vicinity
Stability and reactivity
Chemical Stability: Stable
Conditions to Avoid: Avoid static discharge and uncontrolled exposure to high temperatures.
Incompatibilities: Avoid contact with strong acids and oxidizing agents.
Hazardous Decomposition Products: Toxic fumes may be released upon thermal decomposition (cyanides, nitrogen oxides, carbon
monoxide).
Hazardous Polymerization: Will not occur.
Disposal considerations
Waste is potentially ignitable.
Dispose of this material in accordance with standard practice for disposal of potentially hazardous materials as required by applicable national, state or local laws. Keep away from drains / Do not empty into drains. Do NOT dump into any sewers, on the ground, or into any body of water.
For disposal within the EC, the appropriate code according to the European Waste Catalogue (EWC) is EU waste code: 07 01 99. Note that disposal regulations may also apply to empty containers and equipment rinsates.
This material must be disposed of in a safe way, as a hazardous waste.
Clean / destroy container at approved facility.
Solids from waste water or air treatment: send to approved hazardous waste incinerator. EU waste code 07 01 99
Absorbents, filter materials, wiping cloths and protective clothing: send offsite for incineration. EU waste code 15 02 02
Containers including drums: send to approved hazardous waste handler. EU waste codes: 15 01 10
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.