Registration Dossier
Registration Dossier
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Reaction mass of tetrasodium (E)-7-((4-(4-chloro-6-(3-(2-(sulfooxy)ethylsulfonyl)phenylamino)-1,3,5-triazin-2-ylamino)-2-ureidophenyl)diazenyl)naphthalene-1,3,6-trisulfonate and (E)-7-((4-(4-chloro-6-(3-(2-(sulfooxy)ethylsulfonyl)phenylamino)-1,3,5-triazin-2-ylamino)-2-ureidophenyl)diazenyl)naphthalene-1,3,6-trisulfonic acid
EC number: 945-219-0 | CAS number: -
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
ErC50 > 101.0 mg/l
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 101 mg/L
Additional information
There are no experimental available data of the target substance, thus the information on the Similar Substance 05 has been taken into account. The structural differences occurring between the target substance and Similar Substance 05 are not expected to significantly impact the toxicity to aquatic algae, thus the read across approach can be considered as representavive and appropriate (details in the document attached to the IUCLID section 13).
Study conducted to test guidance "Algal growth inhibition test" Council Directive (1992) in compliance with GLP.
Exponentially-growing cultures of a species of green algae are exposed to various concentrations of the test substance over several generations under defined conditions.
The test solutions are incubated for a period of 72 hours, during which the cell density in each is measured at every 24 hours. The inhibition of growth and growth rate in relation to a control is determined after 72 hours of incubation.
The test results refer to a concentration of the test substance, which was calculated directly from analytically determined TOC values. According to the relevant product information, 1 mg/L TOC equals to 2.9 mg/L of the main component of the test substance (molecular weight: 859 g/mol).
No toxic effects against algae at 101.4 mg/L were noted on the substance tested.
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