Registration Dossier
Registration Dossier
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EC number: 210-716-7 | CAS number: 621-95-4
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2014
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: well performed OECD study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 014
- Report date:
- 2014
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- no
- Type of method:
- flask method
Test material
- Reference substance name:
- 4,4'-ethylenedianiline
- EC Number:
- 210-716-7
- EC Name:
- 4,4'-ethylenedianiline
- Cas Number:
- 621-95-4
- Molecular formula:
- C14H16N2
- IUPAC Name:
- 4-[2-(4-aminophenyl)ethyl]aniline
- Details on test material:
- purity: 99.8%
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- 48 mg/L
- Temp.:
- 20 °C
- pH:
- > 8.5 - < 8.6
- Details on results:
- Three flasks containing approx. 5 g/l test substance in water were stirred for 5 h at 30 °C.
Subsequently the flasks were stirred at 20 °C for 1 day, 2 days and 3 days, respectively.
After each day the content of one flask was filtered through a 0,45 μm membrane filter. The
content of the test substance in the filtrate was determined by UV/VIS spectroscopy.
Flask No. Equilibration time pH Test substance
at 20°C [h] content [mg/L]
1 24 8.6 50
2 48 8.5 48
3 72 8.6 47
mean 48
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubility is 48 mg/L at 20°C. - Executive summary:
The water solubility of the substance was determined according to OECD guideline 105 (flask method) and was found to be 48 mg/L at 20°C.
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