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Diss Factsheets
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EC number: 204-259-2 | CAS number: 118-55-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Acute aquatic toxicity
Fish, Ictalurus punctatus, LC50 = 1.250 mg/L.
Fish, Pimephales promelas, LC50 = 1.09 mg/L.
Acute aquatic toxicity is normally determined using a fish 96-hour LC50 , a crustacea species 48-hour EC50 and/or an algal species 72- or 96-hour EC50. These species cover a range of trophic levels and taxa and are considered as surrogate for all aquatic organisms. For phenyl salicylate are only available LC50 on fish.
Overall, available data are inconclusive since ecotoxicological data are not available for crustacea species and algal species an data on fish are just over 1 mg/L.
Chronic aquatic toxicity
Chronic aquatic toxicity data are not available. Acute aquatic toxity data are available for fish:
Fish, Ictalurus punctatus, LC50 = 1.250 mg/L.
Fish, Pimephales promelas, LC50 = 1.09 mg/L.
Biodegradability data are not available. In accordance with Guidance on the Application of the CLP Criteria (version 5.0), in general, no quantitative estimation method (QSAR) for estimating the degree of biodegradability of organic substances is yet sufficiently accurate to unequivocally predict rapid degradation. However, results from such methods may be used to predict that a substance is not rapidly degradable, or be used in a Weight of Evidence approach.
In general, a QSAR prediction that the substance is not rapidly degradable is considered a better documentation for classification than application of a default classification, when no useful degradation data are available.
The biodegradability of Phenyl salicylate has been predicted using START (Structural Alerts for Reactivity in Toxtree) biodegradation and persistence plug-in, which is based on a compilation of structural alerts for environmental persistence and biodegradability. These structural alerts are molecular functional groups or substructures that are known to be linked to the environmental persistence or biodegradability of chemicals. As a result, Phenyl salicylate has been predicted as Class 2 (persistent chemical).
Experimental BCF value is not available and logKow has not been determined. Predicted (KOWWIN Program (v1.68)) logKow is 3.82.
Overall, since (i) the acute toxicity value on fish range form 1-10 mg/L, (ii) the substance cannot be considered as biodegradable and (ii) predicted logkow is close to 4, the substance is classified as Aquatic Chronic H411.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.