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EC number: 931-275-3 | CAS number: 1125503-33-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
A. BIODEGRADATION IN WATER - STATIC TESTS
1. OECD 301
Type Screening tests
Results from CO2evolution tests (OECD 301B) show that HYEQS is readily and ultimately biodegradable.
2. OECD 314A 14C-HYEQS Biodegradation test in Sewage Influent
The test was carried out at 3 different concentrations (50, 100, 250 µg/L). After 10d 64% of HYEQS was mineralized, 22% of radioactivity was associated with solids and 14% of HYEQS was still in the influent (mean of the three test concentrations). The kinetic for primary and ultimate degradation was calculated. The half-life for primary degradation was ca. 0.6d and for ultimate degradation ca. 2d.
3. OECD 314B 3H- and 14C-HYEQS Activated sludge Die Away Test
The test was run at a concentration of 1000 µg/L. Removal mechanism for both labelled substances were similar. Overall mass balance was 99.9% for 14C-HYEQS and 108% for 3H-HYEQS. Half-life of primary degradation was ca. 0.5h.The Half-life for mineralization of 14C HYEQS was ca. 41h and for 3H-HYEQS ca. 0.8h.The latter value is a more accurate (less conservative) rate of ultimate biodegradation. Only very polar metabolites remained at the end of the study.
4.OECD 314D 14C-HYEQS River Die Away Test
The test system
consisted of: 89% river water, 10% sewage effluent, and 1% combined
activated sludge liquor. Biodegradation was determined by Liquid
Scintillation Counting of 14C-HYEQS over a 21 day test duration. HYEQS
degraded rapidly with a half-life of 0.61 days for loss of parent. No
parent compound remained by day 5.The half-life of mineralization
was 7.7 days(CO2 evolved), and by day 21 80% of the test
substance had evolved as CO2. After 21 days, 0% remained as parent,
11.6% was present as metabolites, 8.4% was present in the solids, and
80% was evolved CO2.
5. Biodegradation of HYEQS in Sediment
HYEQS Biodegradation in sediment was not tested. But a Half-life of
HYEQS for soil (median of 3 soil half-lives) of 6.2d was derived from an
OECD 307 Aerobic Soil transformation study (see IUCLID Section 5.2.3).
Based on EChA REACH Guidance R.16 Environmental Exposure Assessment,
Section R.16.4.4.5 (May 2008) the HYEQS Soil half-life of 6.2d may also
be applied for aerobic sediment if no other data are available.
B.
BIODEGRADATION IN SEWAGE TREATMENT PLANT – DYNAMIC TEST
OECD
303A HYEQS Simulation Test Activated Sludge Unit -Aerobic Sewage
Treatment
HYEQS was
continuously dosed into the activated sludge unit resulting in an
influent concentration of 200 µg/L (137 µg/L C12 isomer, 50 µg/L C14
isomer). Influent and effluent concentration of HYEQS were measured
daily using LC MS MS (LOQ C12 organic medium = 0.96 µg/L, C14 0.35
µg/L). Already one day after the start of the test the elimination of
HYEQS was > 99.95% for C12 and 99.89% for C14. After 2d biodegradation
of HYEQS was >99%. The biodegradation rate during the plateau phase was
>99.9%.
C. BIODEGRADATION IN SOIL
OECD 307 14C-HYEQS Aerobic Transformation in Soil
The degradation rate of 14C-HYEQS in three aerobic soils was investigated during 62 days. 14C-HYEQS was applied at a rate of 0.45 mg a.i./kg soil dw. using sewage sludge as carrier. The application rate was determined from an exposure modelling using realistic use rates. Soil sampling was done after 2, 4, 8, 15, 28 and 62 days. Further sampling up to 120 days was not necessary due to rapid biodegradation. Significant amounts of radioactive carbon dioxide and bound residues were formed. The total mean recoveries of radioactivity were in the range of 91.2 to 94.9% for the three soils. From the measurements the following DT50 were calculated:
DT50 soil 1 6.2 d (median of all 3 soils),
DT50 soil 2 6.0 d,
DT50 soil 3 13.6 d.
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