Registration Dossier
Registration Dossier
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EC number: 209-592-7 | CAS number: 586-98-1
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Remarks:
- Intravenous
- Type of information:
- other: online database
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Remarks:
- Data obtained from an authoritative secondary source.
Data source
Reference
- Reference Type:
- other: online database
- Title:
- ChemIDplus database: 2-hydroxymethylpyridine
- Year:
- 2 017
- Bibliographic source:
- https://chem.nlm.nih.gov/chemidplus/rn/586-98-1
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Data cited in ChemIDplus database. Only result is provided on the database.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2-pyridylmethanol
- EC Number:
- 209-592-7
- EC Name:
- 2-pyridylmethanol
- Cas Number:
- 586-98-1
- Molecular formula:
- C6H7NO
- IUPAC Name:
- (pyridin-2-yl)methanol
- Test material form:
- liquid
- Details on test material:
- - State: Liquid
- Color: Clear light yellow to orange liquid.
- Moisture content (by KF method): 0.50% (max)
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- No other information provided in the data source.
Administration / exposure
- Route of administration:
- intravenous
- Vehicle:
- not specified
- Details on exposure:
- No other information provided in the data source.
- Doses:
- No data
- No. of animals per sex per dose:
- No data
- Control animals:
- not specified
- Details on study design:
- No other information provided in the data source.
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- ca. 1 000 mg/kg bw
- Based on:
- not specified
- Mortality:
- No data
- Clinical signs:
- No data
- Body weight:
- No data
- Gross pathology:
- No data
- Other findings:
- No other information provided in the data source.
Applicant's summary and conclusion
- Conclusions:
- The LD50 of mouse is found to be 1000 mg/kg bw through intravenous route of administration of 2-hydroxymethylpyridine.
- Executive summary:
The LD50 of mouse is found to be 1000 mg/kg bw through intravenous route of administration of 2-hydroxymethylpyridine.
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