Registration Dossier
Registration Dossier
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EC number: 274-159-1 | CAS number: 69852-45-5
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- This study was conducted between 09 April 2016 and 16 December 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- 30 May 2008
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- 27 JUly 1995
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Water solubility:
- > 92.7 other: %w/w
- Conc. based on:
- test mat.
- Incubation duration:
- ca. 28.5 h
- Temp.:
- 30 °C
- pH:
- > 11.5 - < 13.1
- Remarks on result:
- completely miscible
- Details on results:
- The sample concentration, observations and solution pH for each sample are shown in the table below.
- Conclusions:
- The standard EC A.6 / OECD 105 methodology was not applicable to this test item, due to its miscibility with water. Therefore, testing was carried out by visual appraisal
- Executive summary:
The general physico-chemical properties of 3-[[3-(Dimethylamino)propyl]amino]propanenitrile (TK2710) have been determined.
Water Solubility.
Miscible with water in all proportions at 20.0 ± 0.5 °C, by visual assessment, using a flask method, designed to be compatible with Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.
Reference
Table:
| Sample | Concentration (%w/w) | Observation | Solution pH |
| 1 | 5.25 | Single phase, clear, colorless solution. | 11.5 |
| 2 | 25.1 | Single phase, clear, colorless solution. | 12.2 |
| 3 | 47.4 | Single phase, clear, colorless solution. | 12.6 |
| 4 | 74.2 | Single phase, clear, colorless solution. | 12.7 |
| 5 | 92.7 | Single phase, clear, colorless solution. | 13.1 |
Overall result: Miscible with water in all proportions at 20.0 ± 0.5 °C.
Description of key information
Aradur 1019 was determined to be miscible with water in all proportions at 20.0 +/-0.5°C
Key value for chemical safety assessment
- Water solubility:
- 1 000 g/L
- at the temperature of:
- 20 °C
Additional information
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