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EC number: 207-668-4 | CAS number: 488-10-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- March 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study done to guideline, in compliance with GLP
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.2 (Acute Toxicity for Daphnia)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- yes
- Vehicle:
- no
- Test organisms (species):
- Daphnia magna
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Nominal and measured concentrations:
- Nominal: 10, 18, 32, 56 and 100 mg/l.
Average Measured: 9.7, 19, 39, 58 and 110 mg/l. - Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 45 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: 95% confidence interval ranging from 40-49 mg/L
- Details on results:
- The actual concentrations measured at the start of the test were at the level of 98-135% of nominal and remained stable during the exposure (80-103% of initial at the end of the test).
Because the actual concentration at 32 mg/l deviated more than 20% from the nominal concentration the average exposure concentrations were calculated and the effect parameters were expressed in terms of average exposure concentration. - Validity criteria fulfilled:
- yes
- Executive summary:
Under the conditions of the present study the 48h-EC50 was 45 mg/l based on average exposure concentrations, with a 95% confidence interval ranging from 40-49 mg/l.
Reference
Under the conditions of the present study the 48h-EC50 was 45 mg/l based on average exposure concentrations, with a 95% confidence interval ranging from 40-49 mg/l.
Description of key information
EC50 (48 h) = 45.0 mg/L (geometric mean measured, OECD 202, D. magna)
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 45 mg/L
Additional information
There is one study available, in which the short-term toxicity of (Z)-3-methyl-2-(pent-2-en-1-yl)cyclopent-2-enone (CAS 488-10-8) to aquatic invertebrates was assessed according to the OECD guideline 202 and GLP.
In a static test, Daphnia magna was exposed to the nominal concentrations of 10, 18, 32, 56 and 100 mg/L test item for 48 h. The test item concentrations were analytically verified by GC at the start and end of the test.
The measured test item concentrations at the start of the test were 98 – 135% of nominal and remained stable throughout the exposure (80 – 103% of initial at test end). Because the actual concentration at 32 mg/L deviated more than 20% from the nominal concentration the average exposure concentrations were calculated and the effect parameters were expressed in terms of average exposure concentration. The average exposure concentrations were 9.7, 19, 39, 58 and 110 mg/l, respectively. After 48 h immobilization was observed and resulted in an EC50 (48 h) of 45 mg/L based on average exposure concentrations, with a 95% confidence interval ranging from 40-49 mg/L.
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