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Diss Factsheets
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EC number: 918-984-3 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2004-05-25 to 2004-08-31
- Reliability:
- 2 (reliable with restrictions)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Deviations:
- not specified
- GLP compliance:
- not specified
- Analytical monitoring:
- no
- Details on sampling:
- Not applicable
- Vehicle:
- no
- Details on test solutions:
- The mother solution preparation is carried out at a concentration of 100 mg/L.
The mother solution is diluted in order to obtain a concentration range that permit to calculate the LC50-96 hours. - Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- Little trout.
In cultivation into the laboratory (Minimum acclimation of 2 weeks)
Alimentation: Daily until 24 hours before the test
Fishes length 2,0 +/ 1 cm - Test type:
- not specified
- Water media type:
- not specified
- Limit test:
- no
- Total exposure duration:
- 96 h
- Post exposure observation period:
- No post exposure observation period
- Hardness:
- No data
- Test temperature:
- 21 °C to 25 °C
- pH:
- no data
- Dissolved oxygen:
- no data
- Salinity:
- no data
- Nominal and measured concentrations:
- The test solution must be prepared immediately before introducing fishes.
In the same time than the control, we must test concentrations forming a geometrical series, allowing to obatin 100 % death rate after 96 hours and intermediary series to calculate the LCE50-96 hours. - Details on test conditions:
- 12 to 16 hours light/day
no ventilation during the test
No food during the test - Reference substance (positive control):
- not specified
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Results with reference substance (positive control):
- Not applicable
- Reported statistics and error estimates:
- no data
- Sublethal observations / clinical signs:
Results:
Concentration mg/l Death rate 48 hours 96 hours % (96h) Control 0 0 0 5 fishes / 5 litres 0 0 0 Note: ultrasonic sound 2 min / 100 ml then at 5 L.
- Validity criteria fulfilled:
- yes
- Conclusions:
After a 96 hours incubation, a death rate of 50% of little trouts appears for a > 100 mg/L concentration.
LC50 96 h little trout > 100 mg/L- Executive summary:
The aim of this study was to assess, during a 96 -hour period the toxicity of the test mateial against little trout.
This study follows the OECD guideline n° 203.
A limit test was conduced at 100mg/L on ten animals.
No death were noticed in the test or in the negative control vessel.
Determination, in the conditions definde in this norm, of initial concentration (it means of the concentration at the beginning of the test) that, in 96 hours, kills 50% of the fish tested.
This concentration, called efficient initial inhibitor concentration, is designed by LC50 -96 hours.
After a 96 hours incubation, a death rate of 50% of little trouts appears for a > 100 mg/L concentration.
LC50 96 h little trout > 100 mg/L
Reference
Description of key information
After a 96 hours incubation, a death rate of 50% of little trouts appears for a > 100 mg/L concentration.
LC50 96 h little trout > 100 mg/L
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Dose descriptor:
- LC50
- Effect concentration:
- > 100 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.