Registration Dossier
Registration Dossier
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EC number: 206-376-4 | CAS number: 334-48-5
Carcinogenicity
Administrative data
Description of key information
No data are available for carcinogenicity after oral and dermal exposure and inhalation, respectively.
Key value for chemical safety assessment
Carcinogenicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Additional information
No carcinogenicity study is available for decanoic acid.
Studies on mutagenicity/genotoxicity that were either performed with decanoic acid (NTP, 1985) and/or reference substances within the fatty acids category were negative (refer to endpoint genetic toxicity). Moreover, the available long-term studies did not reveal any systemic effects and thus also preneoplastic lesions were not observed.
Fatty acids are found in all living organism fulfilling three fundamental roles. Besides their function as part of molecules like phospholipids and glycolipids important for the cell-structure, they are often precursors of signaling molecules such as prostanoids. The third and best understood role of fatty acid is their role as nutritional energy source. Thus based on the nature of decanoic acid, the knowledge about the toxicokinetics of aliphatic acids, decanoic acid indicates no potential for carcinogenicity.
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