Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Specific investigations: other studies

Currently viewing:

Administrative data

Endpoint:
biochemical or cellular interactions
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: The publication is in accordance with generally accepted scientific principles

Data source

Reference
Reference Type:
publication
Title:
Novel dynamic flow cytoenzymological determination of intracellular esterase inhibition by BCNU and related Isocyanates
Author:
Dive C, Workman P, Watson JV
Year:
1987
Bibliographic source:
Biochem Pharmacol 36: 3731-3738.

Materials and methods

Type of method:
in vitro

Test material

Constituent 1
Chemical structure
Reference substance name:
Butyl isocyanate
EC Number:
203-862-8
EC Name:
Butyl isocyanate
Cas Number:
111-36-4
Molecular formula:
C5H9NO
IUPAC Name:
1-isocyanatobutane
Details on test material:
TS-Freetext:
n-Butyl isocyanate, no data on purity; only source of supply (Sigma) is mentioned

Results and discussion

Applicant's summary and conclusion