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Diss Factsheets
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EC number: 240-012-5 | CAS number: 15876-58-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Justification for type of information:
- Experimental test result performed using standard OECD test guidelines
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Principles of method if other than guideline:
- This study was designed to assess the toxic effects of the test compound on the zebrafish (Danio rerio).The nominal exposure concentration was 0.778 mg/L i.e. the solubility limit of the tested chemical.
- GLP compliance:
- no
- Specific details on test material used for the study:
- - Name of test material(as cited in study report):Dialuminium tris[2-(2,4,5,7-tetrabromo-6-oxido-3-oxoxanthen-9-yl)-3,4,5,6-tetrachlorobenzoate]
- Molecular formula:C20H4Br4Cl4O5 2/3Al
- Physical state:Solid
-Nature of chemical: Organic - Analytical monitoring:
- no
- Details on sampling:
- No data available
- Vehicle:
- not specified
- Details on test solutions:
- No data available
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- TEST ORGANISM
- Common name:Zebra Fish
- Source:Unique Aqua Fish Corner
- Length at study initiation (length definition, mean, range and SD):3.42 cm
- Weight at study initiation (mean and range, SD):0.335 g
- Feeding during test:yes
- Food type:Standard brand feed
- Frequency:once daily
ACCLIMATION
- Acclimation period:7 days
- Acclimation conditions (same as test or not):same as test
- Type and amount of food:Standard brand feed
- Feeding frequency:Once in a day up to sixth day of acclimatization
- Health during acclimation (any mortality observed):No mortality
-Aeration:Continuous aeration was provided
HOUSING
-Duration of housing:15 days
-Photoperiod:12 hours light and 12 hours darkness
-Oxygen content:7.06 (mg/l)
-pH:7.23
-Water temperature:24 °C - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 96 h
- Remarks on exposure duration:
- No data available
- Post exposure observation period:
- 24, 48, 72 and 96 hours.
- Hardness:
- 147 mg of CaCO3
- Test temperature:
- 25°C
- pH:
- 7.17
- Dissolved oxygen:
- No data
- Salinity:
- No data
- Conductivity:
- No data available
- Nominal and measured concentrations:
- Nominal Concentration : Limit Test = 0.778 mg/L
- Details on test conditions:
- -Test vessels:The test vessels used were all plastic aquaria having the water capacity of 5liters.-Photoperiod:12 hours light and 12-hour darkness-Volume of water:2 liters-No. of animals:8 fishes
- Reference substance (positive control):
- not specified
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- > 0.778 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Remarks:
- he LC0 value was considered to be above the solubility limit for the tested chemical.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: No mortalities were found in the control aquaria.
- Details on results:
- Determination or calculation of the median lethal concentrations (LC0) and observations of the symptoms were done after 24, 48, 72 and 96 hours.
- Results with reference substance (positive control):
- No data available
- Reported statistics and error estimates:
- No data available
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The LC0 value was considered to be above the solubility limit for the tested chemical.
- Executive summary:
A fish acute toxicity test according to OECD Guideline 203 was conducted for dialuminiumtris [2-(2, 4, 5, 7-tetrabromo-6 -oxido- 3-oxo xanthen-9-yl)-3, 4, 5, 6-tetrachlorobenzoate]. The nominal exposure concentration was 0.778 mg/L i.e. the solubility limit of the tested chemical. The test organism was zebrafish (Danio rerio). One had two tanks per concentration and 4 fish per tank (8 fish in total per concentration). The water control contained the same number of fish. One observed no mortalities or abnormal behaviour in these fish tanks. The exposure time was 96 hours. The exposed fish were swimming a bit slower after 96 hours. However, no mortalities were observed in the exposure tanks. The LC0 was therefore predicted to be >0.778 mg/L. The LC0 value was considered to be above the solubility limit for the tested chemical.
Reference
Description of key information
A fish acute toxicity test according to OECD Guideline 203 was conducted for dialuminiumtris [2-(2, 4, 5, 7-tetrabromo-6 -oxido- 3-oxo xanthen-9-yl)-3, 4, 5, 6-tetrachlorobenzoate]. The nominal exposure concentration was 0.778 mg/L i.e. the solubility limit of the tested chemical. The test organism was zebrafish (Danio rerio). One had two tanks per concentration and 4 fish per tank (8 fish in total per concentration). The water control contained the same number of fish. One observed no mortalities or abnormal behaviour in these fish tanks. The exposure time was 96 hours. The exposed fish were swimming a bit slower after 96 hours. However, no mortalities were observed in the exposure tanks. The LC0 was therefore predicted to be >0.778 mg/L. The LC0 value was considered to be above the solubility limit for the tested chemical.
Key value for chemical safety assessment
Additional information
A fish acute toxicity test according to OECD Guideline 203 was conducted for dialuminiumtris [2-(2, 4, 5, 7-tetrabromo-6 -oxido- 3-oxo xanthen-9-yl)-3, 4, 5, 6-tetrachlorobenzoate]. The nominal exposure concentration was 0.778 mg/L i.e. the solubility limit of the tested chemical. The test organism was zebrafish (Danio rerio). One had two tanks per concentration and 4 fish per tank (8 fish in total per concentration). The water control contained the same number of fish. One observed no mortalities or abnormal behaviour in these fish tanks. The exposure time was 96 hours. The exposed fish were swimming a bit slower after 96 hours. However, no mortalities were observed in the exposure tanks. The LC0 was therefore predicted to be >0.778 mg/L. The LC0 value was considered to be above the solubility limit for the tested chemical.
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