Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 281-506-0 | CAS number: 83968-28-9
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: data from peer reviewed journals
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Final Report on the Safety Assessment of Basic Violet 1, Basic Violet 3, and Basic Violet 4
- Author:
- Catherine Diamante, Wilma F. Bergfeld, Donald V. Belsito,Curtis D. Klaassen, James G. Marks Jr, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder, and F. Alan Andersen
- Year:
- 2 009
- Bibliographic source:
- International Journal of Toxicology;2009; 28(Suppl 3) 193S-204S
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: as mentioned below
- Principles of method if other than guideline:
- To determine the skin irritation potential of Basic Violet 1
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 8004-87-3
- EC Number:
- 616-846-4
- Cas Number:
- 8004-87-3
- Molecular formula:
- C24H28ClN3
- IUPAC Name:
- 8004-87-3
- Reference substance name:
- Formaldehyde, reaction products with N,N-dimethylbenzenamine and N-methylbenzenamine, oxidized, hydrochlorides
- EC Number:
- 281-506-0
- EC Name:
- Formaldehyde, reaction products with N,N-dimethylbenzenamine and N-methylbenzenamine, oxidized, hydrochlorides
- Cas Number:
- 83968-28-9
- Molecular formula:
- C24H28ClN3
- IUPAC Name:
- Formaldehyde, reaction products with N,N-dimethylbenzenamine and N-methylbenzenamine, oxidized, hydrochlorides
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- Name of the test chemical: C.I. Basic Violet 1
Molecular formula: C24H28ClN3
Constituent 1
Constituent 2
Test animals
- Species:
- other: mammals
- Details on test animals or test system and environmental conditions:
- no data
Test system
- Type of coverage:
- other: no data
- Preparation of test site:
- other: no data
- Amount / concentration applied:
- no data
- Duration of treatment / exposure:
- no data
- Observation period:
- no data
Results and discussion
In vivo
Results
- Irritation parameter:
- overall irritation score
- Basis:
- mean
- Remarks on result:
- other: no signs of irritation observed
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Conclusions:
- Skin irritation study was carried out on mammals to determine the irritation potency of Basic Violet 1.
Basic Violet 1 did not cause any dermal irritation. - Executive summary:
Skin irritation study was carried out on mammals to determine the irritation potency of Basic Violet 1.Basic Violet 1 did not cause any dermal irritation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
