Registration Dossier
Registration Dossier
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EC number: 259-839-8 | CAS number: 55819-71-1
Vapour pressure
Administrative data
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 01 October 2014-08 January 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP-compliant study in accordance with EC A.4, OECD 104 and EPA OPPTS 830.7950.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
- Report date:
- 2015
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- (2009)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- (2006)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7950 (Vapor Pressure)
- Version / remarks:
- (1996)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- other: Effusion method: isothermal thermogravimetry
Test material
- Reference substance name:
- DL-serinohydrazide monohydrochloride
- EC Number:
- 259-839-8
- EC Name:
- DL-serinohydrazide monohydrochloride
- Cas Number:
- 55819-71-1
- Molecular formula:
- C3H9N3O2.ClH
- IUPAC Name:
- 2-amino-3-hydroxy-propanehydrazide;hydrochloride
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- - Name of test material (as cited in study report): DL Serine hydrazide
- Molecular formula: C3H9N3O2.HCl
- Molecular weight: 155.6 g/mol
- Description: White powder
- Storage condition of test material: At room temperature in the dark under nitrogen
- Expiration date of the lot/batch: 22 April 2016
Constituent 1
Results and discussion
Vapour pressureopen allclose all
- Temp.:
- 20 °C
- Vapour pressure:
- < 1.5 other: E-03 Pa
- Temp.:
- 25 °C
- Vapour pressure:
- < 9.6 other: E-03 Pa
Any other information on results incl. tables
Results of the isothermal TGA analysis
Experiment |
Temperature |
Weight loss |
¿T |
|
|
|
|
1 |
110 |
-0.6828 |
-8.15E-05 |
2 |
|
-0.5129 |
-6.12E-05 |
|
|
|
|
1 |
120 |
-0.4135 |
-4.94E-05 |
2 |
|
-0.4053 |
-4.84E-05 |
|
|
|
|
1 |
130 |
-0.3869 |
-4.62E-05 |
2 |
|
-0.1225 |
-1.46E-05 |
|
|
|
|
1 |
140 |
-0.06479 |
-7.73E-06 |
2 |
|
0.06603 |
7.78 E-06 |
The test substance weight losses measured at 110°C, 120°C, 130°C and 140°C were lower than the weight losses of hexachlorobenzene at the same temperatures. From this it was concluded that vapour pressure of the test substance is lower than the vapour pressure of hexachlorobenzene.
Applicant's summary and conclusion
- Conclusions:
- In a GLP-compliant study in accordance with EC A.4, OECD 104 and EPA OPPTS 830.7950 using the isothermal thermogravimetric effusion method, the vapour pressure of the substance at 25°C has been determined as < 9.6E-03 Pa (<1.5E-03 Pa at 20°C).
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