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EC number: 486-670-9 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Oxidising properties
Administrative data
Link to relevant study record(s)
- Endpoint:
- oxidising liquids
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 12 October to 14 December 2010
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Remarks:
- The study was conducted according to an internationally recognised method, and under GLP. No deviation affected the quality of the study. The substance is adequately identified, but details on composition are missing. Therefore validation applies with restrictions.
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.21 (Oxidising Properties (Liquids))
- Deviations:
- no
- Principles of method if other than guideline:
- Not applicable
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- 12 Jan. 2007
- Contact with:
- powdered cellulose
- Duration of test (contact time):
- 120 s
- Key result
- Sample tested:
- test mixture 1:1
- Remarks:
- 2.5 g of the liquid test item mixed with 2.5 g of dried cellulose
- Parameter:
- mean pressure rise time
- Result:
- >= 27 s
- Sample tested:
- reference mixture with 65% nitric acid + cellulose (1:1 ratio)
- Parameter:
- mean pressure rise time
- Result:
- 6.65 s
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The test item is Not an oxidizing liquid, based on slow pressure rise.
- Executive summary:
The oxidising properties of the test item were tested under GLP, according to the EU A.21 guideline.
For the test item, five independent experiments were performed. In none of the experiments, the bursting disc was damaged. For the reference item nitric acid, five independent experiments were performed, too.
A 1:1 mixture with cellulose was used. In the five replicate the increase in pressure was very limited, and did not even reach the lower pressure limit for the determination. The observed increase was attributed to the warming of the mixture in the vessel.
The reference mixture showed a fast increase in pressure: 2070 kPa were surpassed within less than seven seconds in all five experiments.
Test item must be considered as not oxidising, because the pressure raise of a mixture of it with cellulose 1:1 shows no faster increase than the reference mixture of nitric acid and cellulose 1:1.
The test item is classified to be not oxidising under test conditions.
Reference
Time Intervals: The time intervals which were recorded between the lower pressure value (690 kPa) and the upper pressure value (2070 kPa) in each experiment are presented in the following table:
Table 4.15/1: Time Intervals
Content of Test System |
Experiment No. |
Time lapse between 690 kPa and 2070 kPa [s] |
Mean time lapse [s] |
Difference to Mean [%] |
Test Item and Cellulose |
1 |
> |
35 |
- |
2 |
27 |
23% |
||
3 |
36 |
-3% |
||
4 |
> |
- |
||
5 |
42 |
-20% |
||
Reference Item Nitric Acid and Cellulose |
1 |
6.90 |
6.65 |
-3.8% |
2 |
6.74 |
-1.4% |
||
3 |
6.09 |
8.4% |
||
4 |
6.89 |
-3.6% |
||
5 |
6.67 |
-0.3% |
> means that the pressure of 2070 kPa has never been reached during the test time (60 s)
Result: The test item is considered as not oxidising, as the increase in pressure took place very slowly, taking much more time than the reference mixture.
Validity: In a series of five trials, no result should differ by more than 30 % from the arithmetic mean. Results that differ by more than 30 % from the mean should be discarded, the mixing and filling procedure is improved and the testing is repeated.
For the reference item, no result differed by more than 30% from the mean.
The results for the test item showed three experiments which reached the 2070 kPa and two which did not. In the three experiments with the test item mixture where an increase in pressure above 2070 kPa was found, the three values showed no greater difference than 23%.
Discussion:
All validity criteria were met.
No signs of oxidising properties of the test item were detected.
The reference item showed oxidising properties very clearly and with good repeatability.
No observations were made which might cause doubts concerning the validity of the study outcome.
The result of the test is considered valid.
Description of key information
Pressure rise slower than reference, in a 1:1 mixture with cellulose (experimental).
Key value for chemical safety assessment
- Oxidising properties:
- non oxidising
Additional information
A reliable experimental study, conducted according to a recognized EC method and under GLP, is available.
Despite minor restrictions due to incomplete test item identification, it is considered as key study, and the result is retained as key data.
Justification for classification or non-classification
According to CLP and GHS criteria, the time for pressure rise of a 1:1 mixture of test substance with cellulose was longer than the less sensitive reference substance, therefore the substance is NOT considered as an oxidising liquid.
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