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EC number: 203-868-0 | CAS number: 111-42-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Based on lowest reliable acute toxicity values for aquatic species diethanolamine is considered to be toxic for aquatic organisms:
Additional information
Short-term toxicity to fish
The lowest effect value was determined in a guideline study (Environment Canada EPS 1/RM/9, 1990/1996) with Oncorhynchus mykiss. The 96-h LC50 was 460 mg/L (nominal, analytically verified; PTAC, 2006).
Based on this result, diethanolamine is with high probability acutely not harmful to fish.
Long-term toxicity to fish
no data available
Short-term toxicity to aquatic invertebrates
A static acute immobilisation study performed according to ASTM Standard E729-80 with Ceriodaphnia dubia was selected as key study (Cowgill et al., 1985). The 48-h EC50 was determined to be 30.1 mg/L.
Based on this result, diethanolamine is considered to be acutely harmful to aquatic invertebrates.
Long-term toxicity to aquatic invertebrates
The long-term toxicity of diethanolamine on aquatic invertebrates was assessed in a semi-static study conducted according to the draft EEC guideline XI/681/86 "Prolonged toxicity study with Daphnia magna: Effects on reproduction" (BASF AG, 1992) following GLP and with analytically verified test concentrations. The effect values were recalculated using ToxRat Professional v2.10. The EC10 after 21 days of exposure based on reproduction was determined to be 1.05 mg/L (nominal).
It can be concluded that long-term effects on aquatic invertebrates are not to be expected
Toxicity to aquatic algae and cyanobacteria
The most sensitive result was obtained in a GLP study following the US EPA algal assay bottle test 600/9-78-018 (1978) and using the green algae Pseudokirchneriella subcapitata (formerly Selenastrum capricornutum) (DOW Chemical, 1982).
Test 1: The 72-h ErC10 was recalculated to be 1.4 mg/L; the 72-h ErC50 was determined to be 9.5 mg/L. Test 2: The 72-h ErC10 was recalculated to be 1.1 mg/L; the 72-h ErC50 was determined to be 19 mg/L. Results of test 1 and test 2 were re-evaluated by using ToxRat Professional v2.10.
Based on these results diethanolamine is considered to be acutely toxic for aquatic algae
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