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Diss Factsheets
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EC number: 205-500-4 | CAS number: 141-78-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Ethyl acetate will react with photochemically-produced hydroxyl radicals. Clean atmosphere half-life is 8.3 days and moderately-polluted atmosphere half-life can be estimated as around 2.1 days (both values based on a 12 hour sunlit day). A pseduo-first order rate constant suggested that H-atom abstraction takes place at the alkoxy end of the molecule.
Ethyl acetate is effectively resistant to hydrolysis under neutral and acid conditions but that under increasingly basic conditions, hydrolysis increasingly occurs. At pH9, the half life for hydrolysis is 7.5 days compared to 2 years or longer at pH 7 and below.
When ethyl acetate was assessed at a number of concentrations using a non-adapted domestic sewage innoculum in a freshwater medium, rapid degradation was observed. Based on the results of this study, it meets the criteria to be classified as readily biodegradable. Biodegradation was also assessed using an innoculum prepared from natural salt water and boosted with non-adapted domestic sewage innoculum in an artificial salt water medium. Degradation to a level of 60%over the 20 day experimental period was observed and degradation of 47% reached within 5 days. Other studies also confirm that ethyl acetate is readily biodegradable. Biodegradation of ethyl acetate has also been studied in continuous flow activated sludge reactors. Biodegradability over 6 days was evaluated by ultimate BOD analysis compared to TOC and COD values. The ultimate treatment efficiency for ethyl acetate was 99.9% removal; 93% by biodegradation and 7% stripped (volatilized) from the wastewater. Hydraulic retention time in the reactor was 8 hours. Degradation was also studied in a guideline simulated degradation study for which only the results are available; ethyl acetate showed 100% degradation based on a mean retention time of 3 hours in the reactor.
The substance has a low potential for bioaccumulation (log Kow3).
Distribution modelling suggests that environmental concentrations of ethyl acetate are likely to be very low. Based on emissions modelled using a typical use pattern and default emission factors either from the EU TGD or derived by expert assessment, regional water concentrations are predicted to be less than 32ug/l, soil less than 1.5ug/kg and air concentrations less than 3ppb under extreme worse case assumptions.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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