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EC number: 282-013-3 | CAS number: 84082-68-8 Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Myristica fragrans, Myristicaceae.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Boiling point
Administrative data
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- July 12, 2010/July 28, 2010
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling point/boiling range)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- differential scanning calorimetry
Test material
- Reference substance name:
- Nutmeg Oil - Myristica fragrance oil
- IUPAC Name:
- Nutmeg Oil - Myristica fragrance oil
- Details on test material:
- Identification: Nutmeg Oil - Myristica fragrance oil
Batch Number: 577144
Purity: 100%
Expiry Date: February 17, 2013
Storage Conditions: At room temperature at about 20 °C
Constituent 1
Results and discussion
Boiling point
- Boiling pt.:
- 167.7 °C
- Atm. press.:
- 99.2 kPa
- Decomposition:
- no
Any other information on results incl. tables
The determination of the boiling point / boiling range of the test item was performed according to the EEC Directive 92/69 and Council Regulation (EC) No. 440/2008, A.2 “Boiling temperature" and to the OECD Guideline No. 103: "Boiling point", adopted July 27, 1995.
Preliminary Test
The DSC-curve of the preliminary test (heating rate of 20 °C/min from 25 °C to 400 °C) is shown in attached Figure1. An endothermic heat effect was observed at about 172.0 °C. After the experiment, the sample had lost 98.9% of its mass and a small amount of a brownish residue remained in the sample cup.
Main Tests
In order to determine the boiling point more precisely, further DSC-runs were recorded between 100 °C and 250 °C with a heating rate of 10 °C/min. During these runs, the boiling point was determined to be 167.5 °C and 168.0 °C. The samples lost 91.7% and 87.1% of their mass, respectively. After the measurements a small amount of a brownish residue remained in the sample cup. The DSC curve of the first main test is given in attached Figure2. The results of the thermal analysis are summarized in Table 1.
Table1 Determination of the Boiling Point of Nutmeg Oil - Myristica fragrance oil (Summary)
|
Heating Range [°C] |
Heating Rate [°C/min] |
Boiling Point [°C] |
Boiling Point [K] |
Preliminary Test |
25 - 400 |
20 |
172.0 |
445.2 |
1stMain Test |
100 - 250 |
10 |
167.5 |
440.7 |
2ndMain Test |
100 - 250 |
10 |
168.0 |
441.2 |
Mean of boiling point: |
167.7 |
440.9 |
The mean boiling point was calculated from the bold values (onset point of the endothermic reaction).
The tabulated values represent rounded results obtained by calculation using the exact raw data.
Applicant's summary and conclusion
- Conclusions:
- The boiling point of Nutmeg Oil - Myristica fragrance oil was determined to be 167.7 °C, which is equal to 440.9 K.
The estimated accuracy is ± 0.5 K.
The atmospheric pressure during the boiling point measurements was 99.2 kPa. - Executive summary:
The boiling point of Nutmeg Oil - Myristica fragrance oil was determined to be
167.7 °C,
which is equal to 440.9 K.
The estimated accuracy is ± 0.5 K.
This result was obtained using Differential Scanning Calorimetry (Thermal Analysis) method.
The atmospheric pressure during the measurements was 99.2 kPa.
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