Registration Dossier
Registration Dossier
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EC number: 200-539-3 | CAS number: 62-53-3
Repeated dose toxicity: dermal
Administrative data
- Endpoint:
- repeated dose toxicity: dermal
- Adequacy of study:
- other information
Data source
Reference
- Title:
- No information
- Author:
- Anon., The toxicity of aniline, aniline hydrochloride with|cover letter. DOW Chem. Co., Midland, 29 p. (1940)
Materials and methods
Test material
- Reference substance name:
- Aniline
- EC Number:
- 200-539-3
- EC Name:
- Aniline
- Cas Number:
- 62-53-3
- Molecular formula:
- C6H7N
- IUPAC Name:
- aniline
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Details on exposure:
- Route of Administration: dermal
- Duration of treatment / exposure:
- 20 times in 29 d
Doses / concentrations
- Remarks:
- Doses / Concentrations:
1, 10 or 100 mg/kg bw
Basis:
- Control animals:
- not specified
Results and discussion
Target system / organ toxicity
- Critical effects observed:
- not specified
Any other information on results incl. tables
RS-Freetext:
100 mg/kg: decreased body weight, slight decrease in
erythrocyte count, slight hemosiderosis of the
spleen
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
