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Diss Factsheets
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EC number: 202-327-6 | CAS number: 94-36-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.11 mg/L
Additional information
Two experimental results were available in order to assess the toxicity of Dibenzoyl peroxide to aquatic invertebrates. However, these results were considered as unreliable due to the insufficient documentation or unsuitable test systems. As a consequence, a new test was performed according to EEC method C.1 (1984) and OECD Test Guideline 202 (1984) and GLP criteria. These three studies are summarised below:
- K3 Supporting Study (methodological deficiencies): the acute toxicity to Daphnia magna (water flea) was tested under static conditions for 48 hours in accordance with OECD and EEC guidelines for testing of chemicals, and ECETOC, Monograph 26 (1996). The test was performed in compliance with Good Laboratory Practice (GLP). The WAF (Water Accommodated Fraction) prepared from a 1.00025 g/L solution was tested. The following dilutions were tested: 1:16 - 1:8 - 1:4 - 1:2 and the WAF undiluted. Chemical analyses were performed as NPOC (non-purgeable organic carbon). Based on the NPOC concentration determined at the beginning of the test the concentrations were calculated as indicative values. These indicative values were used to calculate the EC50(48h) resulting in 2.91 mg/I, with 95% confidence limits of 2.72 and 3.11 mg/I.
- K4 Supporting Study (documentation insufficient for assessment): the EC50-48h of Dibenzoyl peroxide was estimated at 0.07 mg/l (NIER, 2001).
- K1 Key Study: results are summarised in table below:
Acute toxicity toDaphnia magna
|
Initial mean measured Dibenzoyl peroxide (mg/L) |
EC50 (48 h) |
0.110 [0.0765, 0.157] |
No observed effect concentration (NOEC) |
0.0765 |
[95% confidence limits]
[95% confidence limits]
Therefore, Dibenzoyl peroxide can be considered as very toxic to aquatic invertebrates.
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