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EC number: 203-049-8 | CAS number: 102-71-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
According to the measured BCF the substance does not significantly accumulate in organisms.
Key value for chemical safety assessment
- BCF (aquatic species):
- 3.9 L/kg ww
Additional information
To determine the bioaccumulative potential of TEA (CAS 102 -71 -6) to aquatic organisms, a study conducted according to the OECD test guideline 305 was performed. Cyprinus carpio was used as test species. The determined BCF in this study was < 3.9 at a concentration of 0.25 mg/l whereas at a concentration of 2.5 mg/l a BCF < 0.4 was measured (MITI 1992).
This experimental result is supported by reliable data calculated by several estimation models. The table below lists all applied (Q)SAR models, the estimated BCF values and basic information on the applicability domain (AD). Detailed information on the model’s results and the AD are given in the endpoint study records of IUCLID Chapter 5.3.1. The selected models comply with the OECD principles for (Q)SAR models.
Summary of relevant information on aquatic bioaccumulation: Predicted BCF values for applied QSAR models sorted by BCF: (AD = Applicability Domain)
Model |
BCF |
In AD |
Restraints |
US EPA T.E.S.T. v4.2.1: Bioaccumulation: Consensus method |
0.5 |
no |
Based on the absolute mean errors (MAE) of the Consensus submodel, the confidence in the prediction is low |
BCFBAF v3.01 (EPI Suite v4.11): Arnot-Gobas BCF, upper trophic, incl. biotransformation |
1.3 |
no |
As the substance ionizes at physiologically relevant pH, the estimation may be less accurate. |
BCF Read-Across v1.1.0 (VEGA v1.1.0) |
1.3 |
yes |
- |
Meylan v1.0.3 (VEGA v1.1.0) |
3 |
no |
- Based on the global AD index, the reliability of the prediction is low (descriptors for this compound have values outside the descriptor range of the compounds of the training set) |
CAESAR v2.1.14 (VEGA v1.1.0) |
3 |
yes |
- |
BCFBAF v3.01 (EPI Suite v4.11): Arnot-Gobas BCF, upper trophic, incl. biotransformation of zero |
3.2 |
no |
As the substance ionizes at physiologically relevant pH, the estimation may be less accurate. |
BCFBAF v3.01 (EPI Suite v4.11): Meylan et al. (1997/1999) |
3.6 |
yes |
- |
BCF baseline model v.03.10 (OASIS Catalogic v5.13.1): incl. mitigating factors |
2.5 |
yes |
- |
BCF baseline model v.03.10(OASIS Catalogic v5.13.1): not considering mitigating factors |
9.2 |
yes |
- |
Considering all reliable models applied the estimated BCF values range from 1.3 to 9.2 L/kg. Based on the available information on the log Kow (log Kow = -2.3 at pH 7.1; measured; BASF AG, 1991) and supported by reliable calculated data, it can be concluded that significant accumulation in organisms is not to be expected.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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