Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-603-9 | CAS number: 108-65-6
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A GLP-study in Daphnia magna according to OECD guideline 211 is available for propylene glycol methyl ether acetate.
Key value for chemical safety assessment
Additional information
The Environment Agency of Japan (1998) carried out a chronic toxicity test under semi-static conditions (renewal: 3 times a week) during 21 days. The exposure concentration was 100 mg/l and was measured by gas chromatography. The measured concentrations were 88.6 to 99.9% of the nominal concentration. Based on the nominal concentrations, the 21-day LC50 was determined to be superior to 100 mg/l. The no observed effect concentration (NOEC) was determined to be ≥ 100 mg/l.
The test report from the Environment Agency of Japan (1998) is not available. Yet, all the data were validated by the Japanese authorities within the OECD SIDS program and will be taken into account for the determination of the PNEC for the aquatic compartment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
