Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 219-433-3 | CAS number: 2436-90-0
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
A study was identified as a Key study (Pelcot, 2010). This study was performed according to theOECD guideline No.429 and in compliance with the GLP. The stimulation index was higher than 3 at 50 and 100 %. The EC3 value for dimethyloctadiene was 41%.
Migrated from Short description of key information:
Sensitising (LLNA, OECD 429, Kr: 1)
Justification for classification or non-classification
As positive responses were observe din an LLNA assay and an EC3 value of 41% was determined, dimethyloctadiene is classified as skin sensitizer in category 1B (H317: May cause an allergic skin reaction) according to the criteria of the CLP Regulation n° 1272/2008 and as skin sensitizer (Xi, R43: May cause sensitization by skin contact) according to the criteria of the Annex VI of Directive 67/548/EC.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
