Registration Dossier
Registration Dossier
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EC number: 202-777-3 | CAS number: 99-66-1
Melting point / freezing point
Administrative data
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- publication
- Title:
- Valproic acid and sodium valproate: comprehensive profile
- Author:
- Alsarra, Al-Omar and Belal
- Year:
- 2 005
- Bibliographic source:
- Profiles of drug substances, excipients, and related methodology, volume 32
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: no information on the method but a Thomas-Hoover capillary melting point apparatus was used
- GLP compliance:
- not specified
- Type of method:
- capillary method
Test material
- Reference substance name:
- Sodium valproate
- EC Number:
- 213-961-8
- EC Name:
- Sodium valproate
- Cas Number:
- 1069-66-5
- Molecular formula:
- C8H16O2.Na
- IUPAC Name:
- sodium 2-propylpentanoate
Constituent 1
Results and discussion
Melting / freezing point
- Key result
- Decomposition:
- no
- Remarks on result:
- not determinable
- Remarks:
- sodium valproate does not melt
Applicant's summary and conclusion
- Conclusions:
- Sodium valproate does not melt, decompose or physically change in the normal working range of the Thomas-Hoover capillary melting point apparatus.
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