Registration Dossier
Registration Dossier
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EC number: 700-991-6 | CAS number: 8007-24-7
Carcinogenicity
Administrative data
Description of key information
A carcinogenicity study has not been proposed as it may be waived under the specific rules for adaptation to testing.
Key value for chemical safety assessment
Carcinogenicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated, Distilled (Distilled Grade) will not be classified for carcinogenicity as genotoxicity studies for this grade and also the other read across source substance Distillation Residue Grade are negative. Furthermore, neoplastic lesions or hyperplasia have not been identified in a 90-day repeated-dose study, and a carcinogenicity study is not required.
Additional information
A carcinogenicity study has not been proposed for Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade) because the substance is not classified as mutagen category 3 nor is there evidence from a 90-day repeated dose toxicity study that the substance is able to induce hyperplasia and/or neoplastic lesions.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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