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EC number: 202-808-0 | CAS number: 99-99-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Oxidising properties
Administrative data
Link to relevant study record(s)
- Endpoint:
- oxidising liquids
- Type of information:
- experimental study
- Remarks:
- expert statement based on an experimental study conducted with the closely related 3-Nitrotoluene (CAS 99-08-1)
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.21 (Oxidising Properties (Liquids))
- Deviations:
- no
- GLP compliance:
- not specified
- Contact with:
- other: cellulose
- Sample tested:
- test mixture as specified
- Remarks:
- mixtures of the sample with cellulose (ratio 1 : 1)
- Parameter:
- mean pressure rise time
- Result:
- 6 850 ms
- Remarks on result:
- other: calculated from given data (see Table below), mean, n=5
- Sample tested:
- reference mixture as specified
- Remarks:
- Reference: 65 % Nitric acid + cellulose (1 : 1 ratio)
- Parameter:
- other: pressure rise time of reference mixture
- Result:
- 2 550 ms
- Remarks on result:
- other: single value
- Interpretation of results:
- GHS criteria not met
- Remarks:
- no oxidising properties
- Executive summary:
Heitkamp D and Keldenich H-P (Currenta), 2009 [study report 2009/01371e]
A test conducted according to the Guideline EC A.21 showed that the mean pressure rise time for 3-nitrotoluene (6850 ms; five run tests) was longer than the pressure rise time for the reference substance (65% nitric acid, 2550 ms; single value). Furthermore, no spontaneous ignition was observed. Therefore, 3-nitrotoluene was found to have no oxidising properties.
Conclusion for 4-nitrotoluene based on the read across with 3-nitrotoluene
The structurally closely related 3-nitrotoluene did not show any oxidising properties in the EC A.21 test. 4-Nitrotoluene is expected to behave similarly, and no testing is required. It is concluded that 4-nitrotoluene has no oxidising properties either.
Reference
3-nitrotoluene (CAS 99-08-1) was found "not to have oxidising properties" after the following results were obtained:
Test run | Sample amount | Maximum pressure | Time for pressure rise from 690 kPa to 2070 kPa | Remarks |
1 | 2,5 g | 2688 kPa | 6875 ms | No spontaneous ignition |
2 | 2,5 g | 2750 kPa | 5250 ms | No spontaneous ignition |
3 | 2,5 g | 2688 kPa | 8125 ms | No spontaneous ignition |
4 | 2,5 g | 2844 kPa | 7875 ms | No spontaneous ignition |
5 | 2,5 g | 2625 kPa | 6125 ms | No spontaneous ignition |
| 2,5 g | 2594 kPa | 2550 ms | Reference: 65 % Nitric acid + cellulose (1 : 1 ratio)
|
Study report 2009/01372e and 2009/01684e:
4-nitrotoluene is expected to behave similarly. It is concluded that 4-nitrotoluene has no oxidsing properties either.
The decomposition behaviour determined by differential thermal analysis (DTA) was very similar for both compounds:
DTA measurement of 4-nitrotoluene (CAS 99-99-0), report 2009/01372e and 2009/01684e
Onset of exotherm: 286 °C
Heat release: 1900 J/g
DTA measurement of 3-nitrotoluene (CAS 99-08-1), 2009/01371e
Onset of exotherm: 275 °C
Heat release: 1950 J/g
Description of key information
Heitkamp D and Keldenich H-P (Currenta), 2009 [study report 2009/01371e]
A test conducted according to the Guideline EC A.21 showed that the mean pressure rise time for 3-nitrotoluene (6850 ms; five run tests) was longer than the pressure rise time for the reference substance (65% nitric acid, 2550 ms; single value). Furthermore, no spontaneous ignition was observed. Therefore, 3-nitrotoluene was found to have no oxidising properties.
Conclusion for 4-nitrotoluene based on the read across with 3-nitrotoluene
The structurally closely related 3-nitrotoluene did not show any oxidising properties in the EC A.21 test. 4-Nitrotoluene is expected to behave similarly, and no testing is required. It is concluded that 4-nitrotoluene has no oxidising properties either.
Key value for chemical safety assessment
- Oxidising properties:
- non oxidising
Additional information
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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