Registration Dossier
Registration Dossier
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EC number: 203-417-8 | CAS number: 106-63-8
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
For the structurally related n-butyl acrylate a NOEC of 0.136 mg/L was determined: NOEC (reproduction) = 0.136 mg/L (Daphnia magna, OECD 211, semi-static).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.136 mg/L
Additional information
There are no data on long-term toxicity towards invertebrates for Isobutyl acrylate. But for the structurally related n-butyl acrylate a 21-day chronic toxicity study is available (BASF SE 2009).
A 21-day Daphnia magna Reproduction Test sponsored by The Acrylate REACH Task Force was performed with n-butyl acrylate under semi-static conditions in accordance with OECD TG 211 and GLP regulations (BASF SE, 2009). Nominal test concentrations were 0, 0.1, 0.22, 0.46, 1.0, and 2.2 mg/L. Since the mean values of n-Butyl Acrylate in M4-medium were found to be in the range of 9.3 – 80.0 % of the nominal concentrations, the effect concentrations were based on the time-weighted mean analytically detected concentrations. The most sensitive effect values were concerning reproduction: NOEC (reproduction): 0.136 mg/L; LOEC (reproduction): 0.457 mg/L. Survival of the parent or young daphnia was not affected, but the growth of the parent animals: NOEC (body length): 0.457 mg/L; LOEC (body length): 1.226 mg/L.
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