Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-980-7 | CAS number: 101-83-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (72 hours): >1 mg/l (nominal concentration) based on growth rate
EC50 (72 hours): 0.38 mg/l (nominal concentration) based on biomass
NOEC (72 hours): 0.016 mg/l (nominal concentration) based on growth rate
LOEC (72 hours): 0.031 mg/l (nominal concentration) based on growth rate
EC10 (72 hours): >0.063-0.125 mg/l (nominal concentration) based on growth rate
EC10 (72 hours): 0.02 mg/l (nominal concentration) based on biomass
(EU Method C.3, static test)
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 1 mg/L
- EC10 or NOEC for freshwater algae:
- 0.016 mg/L
Additional information
GLP-guideline study with algae (Desmodesmus subspicatus) was performed according to the European Directive 67/548/EWG, C.3 “Algal inhibition test”, comparable to OECD TG 201. In a growth inhibition test a 72 h-EC50r of > 1 mg/L for the growth rate and 0.38 mg/L for the integral of biomass was determined (Bayer AG, 1992b). The corresponding 72 h-NOEC was 0.016 mg/L and the 72 h-LOEC was 0.031 mg/L for the growth rate and for biomass 72 h EC10 was 0.2 mg/L.
As the detection limit of the analytical method was 0.5 mg/L, only the highest test concentrations were analysed. The recovery rate was in the range of 76 % to 110 %. For the determination of the effect values the nominal concentrations were used.
For algae the following results were derived from another GLP toxicity study with Pseudokirchneriella subcapitata (= Selenastrum capricornutum) according to OECD TG 201 (EA Japan, 1999d): For growth rate, the 72 h-ErC50 was 23 mg/L and the NOEC 2.0 mg/L (all dicyclohexylamine concentrations measured). For biomass, the 72 h- EbC50 was 9.1 mg/L (95 % confidence limits: 8.4-9.8 mg/L) and the NOEC was 2.0 mg/L.
Although the inhibition rate by the growth rate method was less than 50 % at the highest concentration, the toxicity value was determined as 23 mg/L by extrapolation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.