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EC number: 219-553-6 | CAS number: 2461-15-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.007 mg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.072 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.001 mg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 10 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 286.66 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 28.66 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 57.16 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
A PNECaquatic of 0.0072 mg/l has been derived from 7.2 mg/l (EC50 value-48 h) for effects on daphnia in an acute toxicity test (the lowest short-term EC50 from each of three trophic levels (fish, daphnia and algae)), divided by an assessment factor of 1000.
No measured data are currently available for marine organisms. Therefore, the marine PNEC is derived from data obtained for freshwater species (EC50 = 7.2 mg/l), applying an assessment factor of 10000 to give PNECseawater = 0.00072 mg/l.
The intermittent releases PNEC is derived from lowest value obtained for freshwater species (EL50 = 7.2 mg/l), applying an assessment factor of 100 to give PNECwater,intermittent = 0.072 mg/l.
The PNEC for waste-water treatment is 10 mg/l based on the test concentration 100 mg/l for the toxicity control in ready biodegradability test not inhibiting degradatin and an assessment factor of 10 is applied.
No toxicity data are currently available for sediment-dwelling organisms. Therefore, it is not possible to determine a PNECsed based on measured data. According to the Technical Guidance Document, PNECsed can be calculated by the equilibrium partitioning method. Hence, PNECsed (freshwater) = 286.66 mg/kg will be used for risk characterisation.
No toxicity data are currently available for marine sediment-dwelling organisms and therefore, it is not possible to determine a PNEC sediment (marine water) based on measured data. According to the Technical Guidance Document, PNEC sediment (marine water) can be calculated by the equilibrium partitioning method. Hence, PNEC sediment (marine water) = 28.66 mg/kg will be used for risk characterisation.
No toxicity data are currently available for effects to soil. Therefore, it is not possible to determine a PNECsoil based on measured data. According to the Technical Guidance Document, PNECsoil can be calculated by the equilibrium partitioning method. Hence, PNECsoil = 57.16 mg/kg will be used for risk characterisation.
Summary of the value of PNEC in each compartment.
Compartment | Value of PNEC |
Freshwater | 0.0072 mg/l |
STP micro-organisms | 10 mg/l |
Seawater | 0.00072 mg/l (extrapolation from freshwater) |
intermittent release | 0.072 mg/l (extrapolation from freshwater) |
PNECsediment (freshwater) | 286.66 mg/kg |
PNECsediment (marine water) | 28.66 mg/kg |
PNECsoil | 57.16 mg/kg |
Conclusion on classification
Based on the short-term tests on aquatic organisms, the daphnia was the most sensitive to 2-ethylhexyl glycidyl ether in the three trophic level organisms. The EC50 of 7.2 mg/L is the key value for classification.
The test item attained 0 % degradation after 28 days and therefore, cannot be considered as readily biodegradable under the strict terms and conditions of OECD Guideline No. 301F. The log Kow is 3.83 and the calculated BCF value is 355.
Thus, the test substance shall not be classified in accordance with CLP (Regulation EC No.1272/2008) based on available information.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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