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EC number: 937-237-2 | CAS number: 1370006-50-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The 72-hour LOEC for the growth rate was determined to be 1.0 mg/L (corresponding to a mean measured concentration of 21 μg/L) and the 72-hour NOEC for the growth rate was determined to be 0.32 mg/L (corresponding to a mean measured concentration of 7.6 μg/L) based on water accommodated fractions (WAFs).
In addition a long-term Coupled OECD Confirmatory test (5 weeks) for algae under flow through conditions for the closely related partially unsaturated IQAC, DMS quaternised is available. During the 35d exposure there was no change observed in the measured density of the algae cultures exposed to the test substance doted activated sludge unit. The 35d NOEC was determined to be > 100 μg/L, which is well in tune with the 72 h NOEC of the solvent-free oleic-acid based IQAC, DME quaternised. The Coupled OECD Confirmatory test is considered to be the better model for field conditions in surface waters at the outlet of sewage treatment plants and provide a more realistic scenario of exposure of algae.
Key value for chemical safety assessment
- EC10 or NOEC for freshwater algae:
- 100 µg/L
Additional information
The 72 hour acute toxicity of Pseudokirchneriella subcapitata were
exposed to partially unsaturated IQAC, DMS quaternised under static
conditions in accordance to OECD Guideline 201 (2006). The 72-hour LOEC
for the growth rate was determined to be 1.0 mg/L (corresponding to a
mean measured concentration of 21 μg/L) and the 72-hour NOEC for the
growth rate was determined to be 0.32 mg/L (corresponding to a mean
measured concentration of 7.6 μg/L) based on water accommodated
fractions (WAFs). The 72-hour LOEC for yield was determined to be 0.10
mg/L (corresponding to a mean measured concentration of 2.8 μg/L) and
the 72- hour NOEC for yield was determined to be 0.032 mg/L
(corresponding to a mean measured concentration of 0.52 μg/L) based on
water accommodated fractions (WAFs).
The measured concentrations in the test media of the two lowest test
item treatments with loading rates of 0.010 and 0.032 mg/L were <LOQbio
(limit of quantification, 0.614 μg/L). The measured concentrations at
the loading rates of 0.10, 0.32, 1.0, 3.2, 10 mg/L were 2.2, 6.2, 11, 14
and 22 μg/L, respectively. The biological results were related to the
loading rates of the test item and to mean measured test item
concentrations. There were no compound related phytotoxic effects.
In an acute test with algae according to DIN 38 412 Part 9 a similar result was observed. The EC50 was determined to be EC50 (72 h): ca. 1800 — 4500 μg/L act. ingr. (nominal). This value is based on the biomass and therefore not used for the assessment.
In a 5 weeks long-term toxicity study in a Coupled OECD Confirmatory Test the cultures of Scenedesmus subspicatus CHODAT (new name: Desmodesmus subspicatus) were exposed to the degradation products of the closely related partially unsaturated IQAC, DMS quaternised of an activated sludge unit at 24 °C. There was no change in the measured extinction of the algae cultures exposed to the surfactant doted activated sludge unit during the test period of 5 weeks. Only minor variation was observed. The mean extinction was 0.75 E. Visual inspection of the alga cultures showed optimal green coloured cultures, an indication of high active chlorophyll. Sedimentation of algae was not observed. The culture remained stabile over 5 weeks and no negative effects were observed. In comparison the control culture was somewhat labile, so that it could be concluded that the algae culture exposed to the degradation products was slightly promoted. During the test partially unsaturated IQAC, DMS quaternised, is eliminated in the model activated sludge unit by > 90%. The elimination is calculated to be 97.75% taking into account the inflow into the model activated sludge unit of the test substance with a concentration of 10 mg/l, the dilution of the effluent of the elimination unit in ratio 1:1.25 and the separately determined EC0=0.1 mg/l. Thus a NOEC of >100 μg/L is calculated. This toxicity study is classified as assignable, though only few data are reported.
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