Registration Dossier
Registration Dossier
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EC number: 216-957-4 | CAS number: 1708-29-8
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Non-guideline study, non-GLP, available as unpublished report, limitations in design and/or reporting but otherwise adequate for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 959
- Report date:
- 1959
Materials and methods
- Principles of method if other than guideline:
- Performed according to internal BASF guideline
- GLP compliance:
- no
- Limit test:
- no
Test material
- Reference substance name:
- 2,5-dihydrofuran
- EC Number:
- 216-957-4
- EC Name:
- 2,5-dihydrofuran
- Cas Number:
- 1708-29-8
- Molecular formula:
- C4H6O
- IUPAC Name:
- 2,5-dihydrofuran
- Details on test material:
- - Name of test material (as cited in study report): 2,5-Dihydrofuran
- Physical state: liquid
Constituent 1
Test animals
- Species:
- mouse
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- other: Aqueous emulsion of Tragacanth
- Control animals:
- no
- Details on study design:
- - Duration of observation period following administration: 7 days
- Necropsy of survivors performed: yes
- Other examinations performed: clinical signs
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 0.5 other: cm3/kg
- Based on:
- not specified
- Clinical signs:
- Depression, unsteady gait, slight tremble, eating aversion.
- Gross pathology:
- No effects observed.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
