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EC number: 206-839-0 | CAS number: 381-73-7
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The lethal concentration (LC50) value of difluoroacetic acid in fish (Pimephales promelas) in a 96 hr study on the basis of mortality effect was estimated to be 165.50 mg/L. Based on this prediction it can be inferred that the target chemical is nontoxic to aquatic environment. The BCF value of dodecan-1-ol, ethoxylated reported was not >= 500 as well as the substance was found to be rapidly degradable
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 121.88 mg/L
Additional information
The lethal concentration (LC50) value of difluoroacetic acid in fish (Pimephales promelas) in a 96 hr study on the basis of mortality effect was estimated to be 165.50 mg/L. Based on this prediction it can be inferred that the target chemical is nontoxic to aquatic environment. The BCF value of dodecan-1-ol, ethoxylated reported was not >= 500 as well as the substance was found to be rapidly degradable
No. of studies reviewed for short – term toxicity to fish from reliable sources having Klimisch rating 2 and 4.
The summary of the results are presented below
Sr. No. |
Endpoint |
Effect values |
Basis for effects |
Duration |
Species |
Sources |
1 |
LC50 |
165.50 mg/L |
Mortality |
96 hrs |
Pimephales promelas |
Predicted data from QSAR |
2 |
LC50 |
121.88 mg/L |
Mortality |
96 hrs |
Lepomis macrochirus |
Predicted data from QSAR |
3 |
LC50 |
52695.99 mg/L |
Mortality |
96 hrs |
Fish |
Predicted data from ECOSAR |
4 |
LC50 |
85971.10 mg/L |
Mortality |
96 hrs |
Fish |
Predicted data from ECOSAR |
By applying weight of evidence approach to the test substance difluoroacetic acid, the endpoint value was found to vary between LC50 = 121.88 mg/L to 165.50 mg/L in a 96 hrs. also found 52695.99 mg/L & 52695.99 mg/L at 96 hrs. study on the basis of mortality effect. The BCF value of difluoroacetic acid reported was not >= 500 as well as the substance was found to be rapidly degradable. Since the additional criteria mentioned in the CLP regulation related to BCF, biodegradability and Log Kow is not satisfied thus the substance has not been considered for aquatic toxicity classification.
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