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EC number: 931-745-8 | CAS number: 1335203-21-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
In a study conducted according to OECD 106 (2000), the adsorption and desorption of the test item HH-2014 -548 was indirectly determined in five different soils for different incubation times.
2 mg test item /L (concentration used for adsorption kinetics), 1, 0.2, 0.1 and 0.02 mg test item /L were used for the following durations:
Tier 1: 24h
Tier 2: 0.25h, 0.5h, 1h for all soils
2h, 4h, 6h, 24h for soils LUFA 2.2 and 2.4
Desorption kinetics: 2h, 4h, 24h and 72h
Adsorption isotherms: 1h
The results showed a low desorption of 0.05 to 0.7 % during desorption kinetic experiments and a corresponding high adsorption of nearly 100% in the respective adsorption kintetics experiments, thus it can be concluded that HH-2014 -548 strongly interacts with soils, sediment and suspended matter in natural environment.
In a study to determine the soil sorption with the HPLC-Method it was found that the test item strongly interacted with the analytical column. Based on the results obtained it was concluded that the test substance has a Koc value of higher than the reference substance 2,4-DDT. It corresponds with Koc and log Koc value for the test substance of > 427000 and > 5,63, respectively.
From these findings it can be concluded that oleic-acid based IQAC, DMS quaternised will strongly interact with soils, sediment and suspended matter in natural environment. It is technically not feasible to determine a concrete soil sorption coefficient.
Henry's Law Constant was calculated using EPIWIN v3.20, HENRYWIN v3.10 (bond method) and estimated based on the calculated water solubility and vapour pressure (EPIWIN calculations) according to H=vp/ws gave a Henry's Law Constant to get a hint on the volatilisation potential. The calculated Henry's Law Constants indicate that the substance can be regarded as non-volatile from aqueous solution. Due to missing information about the applicability of the calculation model in respect to the substance under investigation the results should be treated with care.Considering the molecular structure, extremely low vapour pressures for the ionic substances are expected. Therefore volatilisation of the oleic-acid based IQAC, DMS quaternised is negligible.
An extraction study was conducted on paper towel to determine the potential migration of imidazolium quaternary ammonium compound (IQAC) from test materials into food-simulating solvents under exaggerated conditions of use (IQAC levels: 0.15% and 0.36%). The extraction was performed in triplicate using 8% and 50% ethanol as extracting solvents at approx. 250°F for 10 minutes, then approx. 120°F for 24 hours. A HPLC/UV method was developed and validated (LOD: 0.403 µg/in. ²). IQAC was not detected in either the 8% or the 50% ethanol extracts taken immediately after 10 min at 250°F. After further 24 h of extraction, mean values of 0.6 and <0.4 µg/in² were detected in 8 and 50% ethanol at an IQAC concentration of 0.15%. At an IQAC concentration of 0.36% mean values of 1.26 and <0.5 µg/in² were determined. Migration into aqueous food and fatty foods was estimated to be 0.13 and 0.05 ppm. The aqueous food and the fatty food migration values, based on a use level of 0.5%, were calculated to be 0.18 ppm and 0.07 ppm, respectively. Using the food distribution factors for uncoated paper, the concentration in the daily diet is 6.7 ppb and the estimated daily intake would not exceed 0.020 mg/person/day. The test compound was prepared using DMS (dimethyl sulfate) which is known to be a carcinogen. DMS was not found at a level of 4 ppm in oleic-acid based IQAC, DMS quaternised. Based on various assumptions a dietary concentration of 0.01 ppb and a estimated daily intake of 0.03 µg/day can be calculated. This is 50 times lower than the Threshold of Regulation dietary limit of 0.5 ppb for DMS.
In 2000, the FDA approved the use of IQAC at concentration up to 0.5% by weight of the dry paper and paperboard.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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