Registration Dossier
Registration Dossier
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EC number: 613-175-9 | CAS number: 6318-09-8
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 990
- Report date:
- 1990
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- ISO 7346-1 (Determination of the Acute Lethal Toxicity of Substances to a Freshwater Fish [Brachydanio rerio Hamilton-Buchanan (Teleostei, Cyprinidae)] - Part 1: Static Method)
- GLP compliance:
- yes
Test material
- Reference substance name:
- 2,4,6-tris(propan-2-yl)benzene-1,3-diamine
- Cas Number:
- 6318-09-8
- Molecular formula:
- C12H26N2
- IUPAC Name:
- 2,4,6-tris(propan-2-yl)benzene-1,3-diamine
Constituent 1
Test organisms
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
Study design
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 96 h
Test conditions
- Test temperature:
- 21.5 - 22.1 °C
- pH:
- 6.8 - 7.8
- Dissolved oxygen:
- 7.7 - 8.3 mg/l
- Nominal and measured concentrations:
- 10 mg/l
31.6 mg/l
100 mg/l
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- 31.6 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 56.2 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Duration:
- 96 h
- Dose descriptor:
- LC100
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
Any other information on results incl. tables
- Sublethal observations / clinical signs:
concentration control (0 mg/l) duration 0 h 24 h 48 h 72 h 96 h temperature (°C) 22.1 21.7 21.7 21.5 21.5 oxigenium (mg/l 8.3 7.7 7.8 7.7 8.0 oxigenium (%) 97.4 89.7 90.9 89.4 92.9 pH 7.8 6.8 7.0 7.1 7.1 mortality (%) 0 0 0 0 0 concentration 10 mg/l) duration 0 h 24 h 48 h 72 h 96 h temperature (°C) 23.1 22.0 21.7 21.6 21.5 oxigenium (mg/l 8.1 7.0 8.1 8.3 8.4 oxigenium (%) 96.8 82.1 94.4 96.6 97.6 pH 8.1 7.3 7.2 7.4 7.3 mortality (%) 0 0 0 0 0 concentration 31.7 mg/l) duration 0 h 24 h 48 h 72 h 96 h temperature (°C) 22.8 22.0 21.7 21.6 21.5 oxigenium (mg/l 8.2 7.2 8.2 8.4 8.3 oxigenium (%) 97.5 84.4 95.6 97.8 96.4 pH 8.1 7.1 7.1 7.4 7.3 mortality (%) 0 0 0 0 0 concentration 100 mg/l) duration 0 h 24 h - - - temperature (°C) 22.9 22.0 - - - oxigenium (mg/l 8.0 7.5 - - - oxigenium (%) 95.2 87.9 - - - pH 8.1 7.1 - - - mortality (%) 0 100 - - -
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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