Registration Dossier
Registration Dossier
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EC number: 236-537-4 | CAS number: 13423-15-9
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
NOEC (33-day) Freshwater Fish: 108 mg/L, based on read-across to Tetrahydrofuran and a 2-fold safety factor
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 108 mg/L
Additional information
The hazard assessment of Tetrahydro-3-methylfuran reveals neither a need to classify the substance as dangerous to the environment, nor is it a PBT or vPvB substance, nor are there any further indications that the substance may be hazardous to the environment. Therefore, and for reasons of animal welfare, a chronic test in fish has not been performed. This conclusion is supported by testing of a closely related analog substance, tetrahydrofuran (CAS# 109-99-9), to examine the effects on hatching rate, growth, and survival in early-life stage fathead minnows (Pimephales promelas) over 33 days in a flow-through test which yielded a NOEC of 216 mg/L (Call, 1985). Applying a safety factor of 2, as suggested in the justification for read across document, yields a NOEC of 108 mg/L suggesting a low degree of chronic toxicity to freshwater fish.
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