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Diss Factsheets
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EC number: 903-945-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Based on experimental data on each constituent, the reaction mass is considered as harmful to fish with a 96h LC50 between 60 and 100 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 60 mg/L
Additional information
No data on acute toxicity to fish is available on the reaction mass of chlorodifluoroacetic acid (CDFA) and trifluoroacetic acid (TFA).
The following data are available on each constituent:
For CDFA, in the preliminary range-finding study of a 14-day fish toxicity test, groups of 10 fish (Danio rerio) were exposed to the test solutions with nominal active ingredient concentration of 100, 80 and 60 mg/L. Synchronously one control group was conducted in test water without the test item. Test duration was 96 hours. Once the test started, the mortalities of the fish were recorded at 24, 48, 72 and 96h. Dead fish were removed at least once daily and discarded. Mortality was observed as follows: 30% at 60 mg/L, 50% at 80 mg/L and 100% at 100 mg/L. Based on these results, the LC50 (96h) was considered between 60 and 100 mg/L.
These results were confirmed in the main study which shows, during 14 days of exposure, no mortality at 40 mg/l and 30% mortality at the highest tested concentration of 60 mg/L (see the section on fish long term toxicity data). Therefore CDFA is harmful to fish.
For TFA, in a 96-h acute toxicity study under static conditions following the OECD Guideline 203, Zebrafish (Danio rerio, n=10) were exposed in a limit test at 1200 and 0 mg/l of trifluoroacetate sodium (i.e. 999 mg/l of TFA) in duplicates. No mortality was observed, demonstrating that LC50(96h) is > 999 mg/l and NOEC = 999 mg/l of TFA. All validity criteria were fulfilled, i.e. mortality in fish control < 10%, constant conditions were maintained throughout the test, dissolved oxygen concentration was >= 60% of the air saturation value throughout the test, and tested concentration has been maintained for at least 80% of the nominal concentration throughout the test.
Considering that the reaction mass of chlorodifluoroacetic acid (CDFA) and trifluoroacetic acid (TFA) is mainly composed of CDFA which is the more toxic of the two constituents, the reaction mass is considered as harmful to fish.
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