Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Based on the outcome of a Klimisch-1-rated 28 days oral repeated dose toxicity study (NOAEL = 200 mg/kg/d, LOAEL = 900 mg/kg/d) , the substance needs not to be classified as to its repeated dose toxicity properties.

Key value for chemical safety assessment

Repeated dose toxicity: via oral route - systemic effects

Endpoint conclusion
Dose descriptor:
NOAEL
200 mg/kg bw/day

Additional information

At the treatment levels used, a No Observed Effect Level of 50 mg/kg/day was established. Furthermore the dose levels 200 mg/kg/d and 900 mg/kg/d are to be considered as NOAEL and LOAEL, respectively.

Justification for classification or non-classification

Based on the study outcome, the substance is not to be classified as to its repeated dose toxicity properties.