Registration Dossier
Registration Dossier
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EC number: 270-296-6 | CAS number: 68424-35-1
Endpoint summary
Administrative data
Description of key information
Calcium is not expected to show acute toxic effects via oral and dermal route.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Based on a weight of evidence, the acute oral toxicity of inorganic calcium salts can safely be assumed to be above the level for classification. No adverse effects in humans are reported up to the upper intake level of 2500 mg/day. Further, two references on (non-guideline compliant) acute oral toxicity in animals do not report any adverse effects leading to a classification as acute orally toxic, thus testing for acute oral toxicity is considered scientifically unjustified for animal welfare reason.
Justification for selection of acute toxicity – oral endpoint
Weight of evidence information.
Justification for classification or non-classification
The available information indicates that inorganic calcium salts are not acutely toxic or harmful. Therefore, classification of inorganic calcium salts for acute toxicity is not warranted.
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