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Diss Factsheets
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EC number: 904-155-3 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
In a 48 hr GLP acute toxicity study, Daphnia magna showed to have an EC50 value greater than 100 mg HB TMP/L.
In a 72 hour GLP acute toxicity study, cultures of Desmodesmus subcapitus showed to have a 72 -hour EyC50 (Cell density/biomass) and ErC50 (growth rate) greater than 100 mg HB TMP/L.
In a 3 hour GLP study performed according to OECD 209 (2010), the effect of HB TMP on the respiration of activated sewage sludge micro-organisms gave a 3 Hour EC50 value of greater than 1000 mg/L. The No Observed Effect Concentration (NOEC) after 3 hours exposure was 1000 mg/L.
Additional information
The 48 hr-acute toxicity of HB TMP to Daphnia magna flow through conditions. Test species were exposed to potassium dichromate and the test chemical at nominal concentration of 0, 4, 6, 10, 22, 46, and 100 mg/L for 48 hr. Immobilisation and sublethal effects were observed daily. The 48 hour EC50 was greater than 100 mg/l. Based on the results of this study, HB TMP would not be classified as toxic to Daphnia magna to in accordance with the CLP classification.
In a 72 hour GLP acute toxicity study, cultures of Desmodesmus subcapitus were exposed to HB TMP at nominal concentrations of 0 (control), 1, 3.2, 10, 32, and 100mg/L flow-through conditions in accordance with the OECD guideline 201 (Version 23 March 2006). Two experiments were performed. In the 1st experiment, both validity criteria (coefficient of variation of the daily growth rates and coefficient of variation of average growth) were not met. Therefore, the experiment was aborted and repeated under the same conditions like the first experiment. The results of the 1st experiment are not stated, but will be kept together with the other raw data in the GLP archive of the test facility. There were no compound related phytotoxic effects. Based on the nominal test concentrations, both the 72-hour EyC50(cell density/biomass) and ErC50(growth rate) were determined to be greater than 100 mg/L.
In a 3 hour GLP study performed according to OECD 209 (2010), activated sewage sludge was exposed to an aqueous dispersion of HB TMP at concentrations of 0, 10, 100 and 1000 mg/L for a period of 3 hours. Less than 13% inhibition was observed in all concentrations. The 3-hour EC50 was estimated to be >1000 mg/L, and the 3-hour NOEC was 1000 mg/L.
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