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Diss Factsheets
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EC number: 939-511-7 | CAS number: 1064698-37-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
PTBA is not expected to be toxic to algae at the limit of solubility (0.710 µg/L) by readacross from category members FC-770 and PMM. No toxicity was observed to P. subcapitata in OECD201 assays tested at the limit of media solubility. These category member results are considered applicable to PTBA.
Key value for chemical safety assessment
Additional information
PTBA is the least water soluble member of the Perfluorinated Organic Chemicals, C5-C18 category. Because these substances exhibit similarity in their physicochemical properties and toxicological properties in mammals, and because available data indicates that parent molecules are not reactive toward biological molecules and cannot undergo bioactivation by normal enzymatic processes, they can be considered members of a chemical category. Data gaps for ecological toxicity can therefore be addressed by read-across and/or trend analysis between category members. Reliable OECD201 studies are available for algae toxicity of category members perfluoromethyl morpholine (PMM), and FC-770. In both cases, EC50s (72-h and 48-h, respectively) were in excess of the maximum achievable test substance concentrations. Analytically determined test substance concentrations are not reasonable to use for readacross since the solubilities of PMM and FC-770 are substantially higher than that of PTBA. Lack of toxicity at the limit of solubility is read across qualitatively to PTBA. The solubility of PTBA was determined to be 0.710 µg/L in organism-free Daphnia medium controls during the short-term toxicity test. This value is greater than the measured PTBA solubility in water (<0.06 µg/L) but less than the analytically determined concentrations in medium containing live daphnids. The organism-free medium solubility value is understood to be better representative of PTBA solubility in natural waters, and avoids potential impacts on the analytical result by the action of living organisms. Therefore, 0.710 µg/L is accepted as the basis for estimating the highest possible exposure concentration of PTBA in order to define the EC50.
Please see IUCLID section 13 for a matrix of aquatic toxicity data for members of the Perfluorinated Organic Chemicals C5-C18 category.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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