Registration Dossier
Registration Dossier
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EC number: 210-249-9 | CAS number: 611-07-4
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 984
- Report date:
- 1984
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EPA OPP 81-1 (Acute Oral Toxicity)
- GLP compliance:
- yes
- Test type:
- standard acute method
Test material
- Reference substance name:
- 5-chloro-2-nitrophenol
- EC Number:
- 210-249-9
- EC Name:
- 5-chloro-2-nitrophenol
- Cas Number:
- 611-07-4
- Molecular formula:
- C6H4ClNO3
- IUPAC Name:
- 5-chloro-2-nitrophenol
- Test material form:
- solid: crystalline
- Details on test material:
- Purity: 87.5%
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- other: sesame oil
Results and discussion
Effect levelsopen allclose all
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- 1 000 mg/kg bw
- Based on:
- test mat.
- 95% CL:
- 525 - 1 910
- Sex:
- female
- Dose descriptor:
- LD50
- Effect level:
- 1 100 mg/kg bw
- Based on:
- test mat.
- 95% CL:
- 608 - 2 240
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- 1 050 mg/kg bw
- Based on:
- test mat.
- 95% CL:
- 746 - 1 550
Applicant's summary and conclusion
- Interpretation of results:
- harmful
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The test item is considered to be harmful following acute oral exposure.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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