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EC number: 237-523-0 | CAS number: 13825-74-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- no data available: testing technically not feasible
Marine water
- Hazard assessment conclusion:
- no data available: testing technically not feasible
STP
- Hazard assessment conclusion:
- no data: aquatic toxicity unlikely
Sediment (freshwater)
- Hazard assessment conclusion:
- no data available: testing technically not feasible
Sediment (marine water)
- Hazard assessment conclusion:
- no data available: testing technically not feasible
Hazard for air
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- no data available: testing technically not feasible
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Effects caused by target chemical titanium oxide sulphate were assessed based on its stable, final hydrolysis products, as they are formed quickly in contact with humidity and therefore virtually in all relevant environmental media. During hydrolysis, sulphuric acid is being formed and thus pH effects may occur. However this is not regarded as true toxicity and is excluded from assessment, which is in accordance with the endpoint related test protocols. Solely the guidance on activated sludge respiration inhibition testing (OECD TGD 209) does not exclude the observation without pH adjustment. Thus read across to sulphuric acid and to the other transformation product, titanium dioxide was made in order to assess the potential effects to activated sludge caused by pH. As pH effects are more than three orders of magnitude higher than the one of the other transformation product it was concluded that acidity dominates rather than modifies the combined effect. Accordingly the assessment is being based on read across from titanium dioxide.
The titanium dioxide formed during hydrolysis is insoluble in water (< 1 µg/L). In order to assess effects of the formed microdisperse particles, the experiments with this test item used generally Water Accommodated Fractions (WAFs) together with the insoluble material in excess. In such experiments no relevant ecotoxic effects were being observed.
Conclusion on classification
Even though testing of target chemical titanium oxide sulphate itself is technically not feasible due to its hydrolytic instability, the hazard assessment could be accomplished on the basis of read across from the transformation products. The relevant transformation product for the effects on algae, daphnids or crustacea, and fish is titanium dioxide in the rutil modification. As evidenced experimentally by studies conform to guidelines, titanium dioxide is not acute toxic or chronic toxic to algae, daphnids and fish in so far as no 50% effect level is reached up to the water solubility level, which was determined according to OECD Environmental Health and Safety Publications Series on testing and assessment no. 29 (Guidance document on transformation/dissolution of metals and metal compounds in aqueous media). Brouwers (2009) found the solubility below the level of detection of the analytical method, i.e. < 1 µg/L at pH 6, 7, and 8. Bioaccumulation of titanium species was likewise not observed. Therefore no classification of target substance titanium oxide sulphate as to its ecotoxicity properties applies.
Brouwers T (2009). 24h screening transformation/dissolution test of Chloride reactor discharge at a 100 mg/L loading in a standard aqueous medium at pH 6, 7 and 8. testing laboratory: ECTX consult bvba, Bergstraat 73, B3500 Hasselt/ analytical phase: Servaco nv, Tramstraat 2, B8560 Wevelgem.
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