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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
publication
Title:
Antibiotics Annual. Vol. 3, Pg. 534, 1955/1956.
Year:
1955
Bibliographic source:
Antibiotics Annual. Vol. 3, Pg. 534, 1955/1956.

Materials and methods

Test animals

Species:
rat

Results and discussion

Effect levels
Key result
Dose descriptor:
LD50
Effect level:
> 2 220 mg/kg bw
Remarks on result:
other: LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Clinical signs:
other: other:

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met