Registration Dossier
Registration Dossier
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EC number: 218-507-2 | CAS number: 2167-23-9
Endpoint summary
Administrative data
Description of key information
Several aquatic studies have been performed.
An estimation of the LC50 for adult fish species was made. The effects on newly fertilized zebra fish eggs and hatchlings over an exposure period of 96 hours according to the OECD 236 were determined. The test substance has a predicted adult fish LC50 of > 10 mg/L (above the water solubility of 8.3 mg/L).
ECOSAR is used as qualitative weight of evidence that fish is not the most sensitive endpoint. As the log Kow is > 5 (5.4), no effects at saturation are predicted for short-term daphnia, algae and short-term fish.
The acute toxicity of the test chemical to Daphnia magna was determined according to OECD 202 in a semi-static system over an exposure period of 48 hours.
50% effect on mobility was not reached, therefore EL50 (48h) may be expressed as >150 mg/L loading rate (the highest test concentration).
The toxicity of the test chemical to an exponentially growing culture of P. subcapitata was determined over an exposure period of 72 hours. The study was performed as a limit test at 100 mg/L loading according to OECD 201 under GLP. No significant effects were found, therefore ErL50 and ErL10 (72h) may be expressed as >100 mg/L loading rate.
Toxicity to microorganisms was determined as well in an activated sludge respiration inhibition test was performed according to OECD 209.
The EC50 (3h) of the substance for activated sludge is greater than 20 mg/L. The EC10 is also greater than 20 mg/L.
Additional information
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